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[肝炎患者骨髓细胞中的HBV感染情况]

[The conditions of HBV infection in myeloid cells in patients with hepatitis].

作者信息

Gao Z X, Zhang Y W, Chen Y J

机构信息

Changchun Hospital for Infectious Diseases.

出版信息

Zhonghua Nei Ke Za Zhi. 1991 Jan;30(1):24-6, 60.

PMID:2032491
Abstract

In this study, HBsAg, HBcAg and HBV DNA in myeloid cells of 57 patients with hepatitis have been examined by using ABC staining method. The results show that in the myeloid cells of 54 patients with positive HBVM in serum, there are 4 cases with HBV positive antigen, HBcAg has been found in a case of acute hepatitis and HBsAg in a case of chronic hepatitis and a case of liver cirrhosis respectively, HBsAg and HBcAg were found simultaneously in another case of liver cirrhosis. Nothing has been found the myeloid cells of 3 cases with negative HBVM in serum. All these findings suggest that myeloid cells are probably another breeding ground for duplicating HBV.

摘要

本研究采用ABC染色法检测了57例肝炎患者骨髓细胞中的HBsAg、HBcAg和HBV DNA。结果显示,血清HBVM阳性的54例患者骨髓细胞中,有4例HBV阳性抗原,急性肝炎1例发现有HBcAg,慢性肝炎1例及肝硬化1例分别发现有HBsAg,另1例肝硬化同时发现有HBsAg和HBcAg。血清HBVM阴性的3例患者骨髓细胞未发现上述情况。所有这些结果提示,骨髓细胞可能是HBV复制的又一场所。

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