Goldberg W M, Chakrabarti S, Filipich R
Can Med Assoc J. 1966 Jun 11;94(24):1264-8.
Urinary lactic dehydrogenase, alkaline phosphatase and lysozyme determinations were performed on 70 patients with various kidney diseases such as acute and chronic pyelonephritis, acute and chronic glomerulonephritis, idiopathic nephrotic syndrome, diabetic nephropathy, nephrosclerosis, lupus nephritis, analgesic nephropathy, gouty nephropathy, renal tuberculosis, renal lithiasis, and polycystic kidneys. Fifty-three of these patients had elevated levels of urinary lactic dehydrogenase, but this was not of any value in determining the etiology of the renal disease. Similarly, the elevation of alkaline phosphatase in 23 of the 70 had no etiological significance. Neither of these determinations was significant in indicating the degree of renal functional impairment or prognosis. The urinary lysozyme was significantly elevated in only five of the 70 patients and was of no value in indicating the presence or the seriousness of the underlying renal disease.
对70例患有各种肾脏疾病的患者进行了尿乳酸脱氢酶、碱性磷酸酶和溶菌酶测定，这些疾病包括急慢性肾盂肾炎、急慢性肾小球肾炎、特发性肾病综合征、糖尿病肾病、肾硬化症、狼疮性肾炎、镇痛剂肾病、痛风性肾病、肾结核、肾结石和多囊肾。其中53例患者尿乳酸脱氢酶水平升高，但这对确定肾病病因并无价值。同样，70例中有23例碱性磷酸酶升高也无病因学意义。这两项测定在指示肾功能损害程度或预后方面均无显著意义。70例患者中仅有5例尿溶菌酶显著升高，在指示潜在肾脏疾病的存在或严重程度方面并无价值。
