Takegoshi K, Nakanuma Y, Tsukada K, Okuda K
Department of Internal Medicine, Takaoka City Hospital, Japan.
J Clin Gastroenterol. 1991 Apr;13(2):202-4. doi: 10.1097/00004836-199104000-00017.
We report the first case of human T-lymphotropic type 1-associated myelopathy (HAM) linked with primary sclerosing cholangitis (PSC). The patient, a 44-year-old woman, also suffered from ulcerative colitis and polyarthritis. Two years and nine months after the clinical onset of PSC, the coexistence of HAM was shown by neurological manifestations characterized by slowly progressive symmetrical myelopathy, predominantly involving pyramidal tracts, and positive antibodies to human T-lymphotropic virus type 1 in serum as well as in cerebrospinal fluid.
我们报告了首例与原发性硬化性胆管炎（PSC）相关的1型人类嗜T淋巴细胞病毒相关脊髓病（HAM）。该患者为一名44岁女性，还患有溃疡性结肠炎和多关节炎。在PSC临床发病两年零九个月后，HAM的共存表现为以缓慢进展的对称性脊髓病为特征的神经学表现，主要累及锥体束，血清和脑脊液中1型人类嗜T淋巴细胞病毒抗体呈阳性。
