Canadian Field Epidemiology Program, Public Health Agency of Canada, Ottawa, ON, Canada.
Epidemiol Infect. 2010 Dec;138(12):1695-703. doi: 10.1017/S095026881000049X. Epub 2010 Mar 25.
One of the largest reported campylobacteriosis outbreaks in Canada occurred in June 2007 in British Columbia, associated with a mountain bike race that took place in muddy conditions. A retrospective cohort study was conducted and environmental samples were collected and tested. There were 537 racers included in the study and 225 racers (42%) reported diarrhoeal illness after the race. C. jejuni clinical isolates (n=14) were found to be identical by multi-locus sequence typing. Although univariate analysis suggested water consumption and mud exposure as significant risk factors, multivariate analysis revealed that on direct ingestion mud was significantly associated with illness (OR 4·08, 95% CI 2·03-8·21). Contaminated mud was thus the most likely source of Campylobacter infection. We identified other unpublished reports of outbreaks associated with bike races in rainy or muddy conditions; these underscore the importance of educating racers and raising public awareness of the risks of mud ingestion.
加拿大最大的报告之一的弯曲杆菌病爆发发生在 2007 年 6 月不列颠哥伦比亚省，与山地自行车比赛有关，该比赛在泥泞条件下举行。进行了回顾性队列研究，并收集和测试了环境样本。研究包括 537 名参赛者，其中 225 名参赛者（42%）在比赛后报告腹泻病。发现 14 株 C. jejuni 临床分离株通过多位点序列分型完全相同。尽管单变量分析表明水的消耗和泥的暴露是重要的危险因素，但多变量分析表明直接摄入泥与疾病显著相关（OR 4.08，95%CI 2.03-8.21）。因此，污染的泥土是弯曲杆菌感染的最可能来源。我们还确定了其他未发表的与多雨或泥泞条件下自行车比赛有关的爆发报告；这些报告强调了教育参赛者和提高公众对摄入泥土风险的认识的重要性。
