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N-甲基取代的三环酰亚胺的还原 Heck 反应。

Reductive Heck reactions of N-methyl-substituted tricyclic imides.

机构信息

Department of Chemistry, Faculty of Art and Sciences, Davutpasa Campus, Yildiz Technical University, 34210 Esenler-Istanbul, Turkey.

出版信息

Molecules. 2010 Mar 4;15(3):1302-8. doi: 10.3390/molecules15031303.

DOI:10.3390/molecules15031303
PMID:20335982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6257395/
Abstract

The palladium-catalyzed hydroarylation of N-methyl-substituted tricyclic imides was studied in order to find a new stereoselective access to a series of new exo-aryl(hetaryl)-substituted tricyclic N-methylimides.

摘要

钯催化的 N-甲基取代的三环亚胺的氢芳基化反应被研究,以寻找一种新的立体选择性方法来合成一系列新的外芳基(杂芳基)取代的三环 N-甲基亚胺。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc4f/6257395/847a7102bcf9/molecules-15-01302-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc4f/6257395/86b00e128043/molecules-15-01302-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc4f/6257395/030f61d7b73d/molecules-15-01302-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc4f/6257395/89bc1121ae28/molecules-15-01302-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc4f/6257395/847a7102bcf9/molecules-15-01302-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc4f/6257395/86b00e128043/molecules-15-01302-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc4f/6257395/030f61d7b73d/molecules-15-01302-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc4f/6257395/89bc1121ae28/molecules-15-01302-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc4f/6257395/847a7102bcf9/molecules-15-01302-g004.jpg

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本文引用的文献

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Bioorg Med Chem Lett. 2009 Mar 1;19(5):1534-8. doi: 10.1016/j.bmcl.2008.07.048. Epub 2008 Jul 17.
2
Structural studies on cycloadducts of furan, 2-methoxyfuran, and 5-trimethylsilylcyclopentadiene with maleic anhydride and N-methylmaleimide.呋喃、2-甲氧基呋喃和5-三甲基硅基环戊二烯与马来酸酐和N-甲基马来酰亚胺的环加成物的结构研究
J Org Chem. 2008 Jan 4;73(1):151-6. doi: 10.1021/jo7018575. Epub 2007 Dec 11.
3
Synthesis, biological activity, and quantitative structure-activity relationship study of azanaphthalimide and arylnaphthalimide derivatives.
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J Med Chem. 2004 Apr 22;47(9):2236-42. doi: 10.1021/jm0310784.
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Modified norcantharidins; synthesis, protein phosphatases 1 and 2A inhibition, and anticancer activity.修饰去甲斑蝥素;合成、蛋白磷酸酶1和2A抑制作用及抗癌活性。
Bioorg Med Chem Lett. 2004 Apr 19;14(8):1969-73. doi: 10.1016/j.bmcl.2004.01.093.
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Structural Investigations into the retro-Diels-Alder Reaction. Experimental and Theoretical Studies.关于逆狄尔斯-阿尔德反应的结构研究。实验与理论研究。
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Farmaco. 2001 Oct;56(10):785-9. doi: 10.1016/s0014-827x(01)01144-2.