Stereoselective synthesis of 3-alkylideneoxindoles via palladium-catalyzed domino reactions.
作者信息
Yanada Reiko, Obika Shingo, Inokuma Tsubasa, Yanada Kazuo, Yamashita Masayuki, Ohta Shunsaku, Takemoto Yoshiji
机构信息
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.
出版信息
J Org Chem. 2005 Aug 19;70(17):6972-5. doi: 10.1021/jo0508604.
PMID:16095329
Abstract
We have developed efficient catalytic methods for the stereoselective and diversity synthesis of various (E)-, (Z)-, and disubstituted 3-alkylideneoxindoles and 3-alkylidenebenzofuran-2-ones via palladium-catalyzed Heck/Suzuki-Miyaura, Heck/Heck, and Heck/carbonylation/Suzuki-Miyaura domino reactions.
摘要
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