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药用植物对引起复杂性尿路感染的病原体的抗菌活性

Antibacterial Activity of Medicinal Plants Against Pathogens causing Complicated Urinary Tract Infections.

作者信息

Sharma Anjana, Chandraker S, Patel V K, Ramteke Padmini

机构信息

Bacteriology Laboratory, Department of Post Graduate Studies and Research in Biological Sciences, R. D. University, Jabalpur-482 001, India.

出版信息

Indian J Pharm Sci. 2009 Mar;71(2):136-9. doi: 10.4103/0250-474X.54279.

Abstract

Seventeen Indian folklore medicinal plants were investigated to evaluate antibacterial activity of aqueous, ethanol and acetone extracts against 66 multidrug resistant isolates of major urinary tract pathogens (Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Enterococcus faecalis) by disc diffusion method. Ethanol extract of Zingiber officinale and Punica granatum showed strong antibacterial activity against Escherichia coli. Ethanol extracts of Terminalia chebula and Ocimum sanctum exhibited antibacterial activity against Klebsiella pneumoniae. Ethanol extract of Cinnamomum cassia showed maximum antibacterial activity against Pseudomonas aeruginosa while ethanol extract of Azadirachta indica and Ocimum sanctum exhibited antibacterial activity against Enterococcus faecalis. The results support the folkloric use of these plants in the treatment of urinary tract infections by the tribals of Mahakoshal region of central India.

摘要

对17种印度民间药用植物进行了研究,采用纸片扩散法评估其水提取物、乙醇提取物和丙酮提取物对66株主要泌尿道病原体(大肠杆菌、肺炎克雷伯菌、铜绿假单胞菌和粪肠球菌)的多重耐药菌株的抗菌活性。姜和石榴的乙醇提取物对大肠杆菌表现出较强的抗菌活性。诃子和罗勒的乙醇提取物对肺炎克雷伯菌具有抗菌活性。肉桂的乙醇提取物对铜绿假单胞菌表现出最大的抗菌活性,而印楝和罗勒的乙醇提取物对粪肠球菌具有抗菌活性。这些结果支持了印度中部马哈科沙尔地区部落将这些植物用于治疗尿路感染的民间用法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac8a/2839399/74e1758f6fbd/IJPhS-71-136-g001.jpg

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