Department of Botany and Microbiology, Gurukula Kangri (Deemed to be University), Haridwar 249404, India.
Department of Microbiology, Faculty of Science and Technology, Mewar University, Chittorgarh 312901, India.
Molecules. 2020 Nov 28;25(23):5593. doi: 10.3390/molecules25235593.
Urinary tract infections (UTIs) are considered to be the most common infections worldwide, having an incidence rate of 40-60% in women. Moreover, the prevalence of this disorder in adult women is 30 times more than in men. UTIs are usually found in many hospitals and clinical practice; as disorders, they are complicated and uncomplicated; in uncomplicated cases, there is no structural or functional abnormality in the urogenital tract. However, obstruction, retention of urine flow and use of catheters increase the complexity. There are several bacteria (e.g., , , , etc.) successfully residing in the tract. The diagnosis must not only be accurate but rapid, so early detection is an important step in the control of UTIs caused by uropathogens. The treatment of UTIs includes appropriate antimicrobial therapy to control the infection and kill the causal microbes inside the body. A long-time usage of antibiotics has resulted in multidrug resistance causing an impediment in treatment. Thus, alternative, combinatorial medication approaches have given some hope. Available treatments considered Homeopathic, Ayurvedic, Unani, and other herbal-based drugs. There are new upcoming roles of nanoparticles in combating UTIs which needs further validation. The role of medicinal plant-based nanotechnology approaches has shown promising results. Therefore, there must be active research in phyto-based therapies of UTIs, such as Ayurvedic Biology.
尿路感染（UTIs）被认为是全球最常见的感染，女性的发病率为 40-60%。此外，成年女性中这种疾病的患病率比男性高 30 倍。UTIs 通常在许多医院和临床实践中发现；作为疾病，它们是复杂的和不复杂的；在不复杂的情况下，尿路没有结构或功能异常。然而，梗阻、尿流潴留和使用导管会增加复杂性。有几种细菌（如、、、等）成功地存在于该部位。诊断不仅必须准确，而且必须迅速，因此早期发现是控制尿路病原体引起的 UTIs 的重要步骤。UTIs 的治疗包括适当的抗菌治疗，以控制感染并杀死体内的致病微生物。抗生素的长期使用导致了多药耐药性，这给治疗带来了障碍。因此，联合用药方法带来了一些希望。现有的治疗方法包括顺势疗法、阿育吠陀、尤纳尼和其他基于草药的药物。纳米颗粒在对抗 UTIs 方面的新作用需要进一步验证。基于植物的纳米技术方法在治疗 UTIs 方面显示出了有希望的结果。因此，必须积极研究基于植物的 UTIs 治疗方法，如阿育吠陀生物学。
