Department of Pediatrics, Turku University Hospital, Turku, Finland.
Eur J Pediatr. 2010 Oct;169(10):1275-7. doi: 10.1007/s00431-010-1187-6. Epub 2010 Mar 25.
In neonates, recurrent group B streptococcal infection is uncommon, and two relapses are extremely rare. We report a case of three distinct episodes of Streptococcus agalactiae bacteremia in a healthy full-term infant over a 4-week period. The newborn had no apparent predisposing condition or infectious focus, and the recurrences occurred after adequate antimicrobial treatment, the second occurring after withdrawal of colonized breast milk. Finally, oral rifampin was combined to his antibiotic regimen, his colonization cultures turned negative, and no further relapses have occurred during the 11-month follow-up. Conclusion In this report, we describe a newborn with two exceptionally rapid recurrences of group B streptococcal septicemias, and who was successfully treated with combining rifampin to the antibiotic regimen.
在新生儿中，复发性 B 组链球菌感染并不常见，两次复发极为罕见。我们报告了一例健康足月婴儿在 4 周内发生三次不同的无乳链球菌菌血症的病例。新生儿没有明显的易患条件或感染灶，且在充分的抗菌治疗后复发，第二次复发发生在被定植的母乳被停用之后。最后，在他的抗生素治疗方案中联合应用利福平，他的定植培养转为阴性，并且在 11 个月的随访中没有再发生复发。结论：在本报告中，我们描述了一例新生儿 B 组链球菌败血症的两次异常快速复发的病例，并且联合应用利福平治疗取得了成功。
