体脂人体测量指标：哪些指标能更好地识别心血管高危人群？西班牙人群的一项比较研究。
Body fat anthropometric indexes: Which of those identify better high cardiovascular risk subjects? A comparative study in Spanish population.
机构信息
Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Madrid, Spain.
Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain.
出版信息
PLoS One. 2019 May 23;14(5):e0216877. doi: 10.1371/journal.pone.0216877. eCollection 2019.
AIM
To determine the association of body mass index (BMI), waist circumference (WC), waist to hip ratio (WHR), waist to height ratio (WHtr) and Body Shape Index (ABSI) with high cardiovascular risk (CVR), as well as to determine whether how strong are these relationships.
MATERIAL AND METHODS
A cross-sectional study was carried out in Spanish Caucasian adults. 3,456 subjects completed the study, 45.78% males, aged < 65 years and non-diabetic subjects. Anthropometric/biochemical variables were measured. We determined ABSI based on WC adjusted for height and weight. High CVR was defined as ≥ 20% according to the Framingham chart, ≥ 5% with the SCORE chart, and ≥ 7.5% with the ACC/AHA guide. Areas under the receiver operating characteristic curves (AUCs) were estimated for each anthropometric measure.
RESULTS
Most significant AUCs in males were: WHtr and ABSI for Framingham ≥ 20% and SCORE ≥ 5%. Also significant were WHtr, WC and ABSI for ACCA/AHA ≥ 7.5%. On the other hand, most significant AUCs in females were: WHtr and WC for Framingham ≥ 20%; and WHtr and WHR for SCORE ≥ 5%, WHtr, and WC for ACC/AHA guide ≥ 7.5%.
CONCLUSIONS
Overall, the best anthropometric index identifying Spanish males and females who are at high risk for CV events is WHtr. ABSI was also found to be a good anthropometric index to predict high CVR in Spanish males according to FR, SCORE and ACC/AHA charts. For Spanish females, WC is a good anthropometric index according to FR and ACC/AHA guide, while WHR is better according to SCORE.
目的
确定身体质量指数（BMI）、腰围（WC）、腰臀比（WHR）、腰高比（WHtr）和身体形状指数（ABSI）与高心血管风险（CVR）的关联，并确定这些关联的强度如何。
材料和方法
这是一项在西班牙白种成年人中进行的横断面研究。3456 名受试者完成了这项研究，其中 45.78%为男性，年龄<65 岁且非糖尿病患者。测量了人体测量/生化变量。我们根据 WC 与身高和体重的比值确定了 ABSI。高 CVR 根据 Framingham 图表定义为≥20%，根据 SCORE 图表定义为≥5%，根据 ACC/AHA 指南定义为≥7.5%。估计了每个人体测量指标的接收者操作特征曲线（AUC）下的面积。
结果
男性中最显著的 AUC 为：WHtr 和 ABSI 用于 Framingham ≥ 20%和 SCORE ≥ 5%；WHtr、WC 和 ABSI 也用于 ACCA/AHA ≥ 7.5%。另一方面，女性中最显著的 AUC 为：WHtr 和 WC 用于 Framingham ≥ 20%；WHtr 和 WHR 用于 SCORE ≥ 5%，WHtr 和 WC 用于 ACC/AHA 指南≥7.5%。
结论
总体而言，识别西班牙男性和女性患心血管事件高风险的最佳人体测量指标是 WHtr。ABSI 也被发现是一种很好的人体测量指标，可以根据 FR、SCORE 和 ACC/AHA 图表预测西班牙男性的高 CVR。对于西班牙女性，WC 是根据 FR 和 ACC/AHA 指南的一个很好的人体测量指标，而 WHR 根据 SCORE 则更好。
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