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小睡与 2 型糖尿病风险增加有关:广州生物库队列研究。

Napping is associated with increased risk of type 2 diabetes: the Guangzhou Biobank Cohort Study.

机构信息

Public Health, Epidemiology and Biostatistics, University of Birmingham, UK.

出版信息

Sleep. 2010 Mar;33(3):402-7. doi: 10.1093/sleep/33.3.402.

DOI:10.1093/sleep/33.3.402
PMID:20337199
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2831435/
Abstract

STUDY OBJECTIVE

Intentional napping is very common, particularly in China. However, there are limited data regarding its potential health effects. We therefore examined the possible relationship between napping and type 2 diabetes.

DESIGN

Cross-sectional analysis of baseline data from the Guangzhou Biobank Cohort Study.

SETTING

Community-based elderly association in Guangzhou, China.

PARTICIPANTS

19,567 Chinese men and women aged 50 years or older.

MEASUREMENTS AND RESULTS

Self-reported frequency of napping was obtained by questionnaire and type 2 diabetes was assessed by fasting blood glucose and/or self-reports of physician diagnosis or treatment. Participants reporting frequent naps (4-6 days/week and daily) were 42% to 52% more likely to have diabetes. The relationships remained essentially unchanged after adjustments were made for demographics, lifestyle and sleep habits, health status, adiposity, and metabolic markers (odds ratio for diabetes 1.36 [95% CI 1.17-1.57] in 4-6 days/week, 1.28 [1.15-1.44] in daily nappers). Similar associations were found between napping and impaired fasting glucose. Removal of those with potential ill health and daytime sleepiness did not alter the observed associations.

CONCLUSIONS

Napping is associated with elevated prevalence of diabetes and impaired fasting glucose in this older Chinese sample. Our finding suggests that it is less likely that diabetes leads to daytime sleepiness. This raises the possibility that napping may increase the risk of diabetes. Confirmation by longitudinal studies is needed.

摘要

研究目的

在中国,人们经常会进行有目的的午睡,这一现象非常普遍。然而,目前有关午睡对健康影响的研究数据非常有限。因此,我们探讨了午睡与 2 型糖尿病之间可能存在的关系。

研究设计

对来自广州生物银行队列研究的基线数据进行横断面分析。

研究地点

中国广州的社区老年人协会。

研究对象

19567 名年龄在 50 岁及以上的中国男女。

测量和结果

通过问卷调查获取参与者午睡频率的自我报告数据,通过空腹血糖和/或医生诊断或治疗报告评估 2 型糖尿病。与每周午睡 1-3 天的参与者相比,每周午睡 4-6 天和每天午睡的参与者发生糖尿病的风险分别增加 42%至 52%。调整人口统计学因素、生活方式和睡眠习惯、健康状况、肥胖和代谢标志物后,这些关系基本保持不变(每周 4-6 天午睡者糖尿病的比值比为 1.36[95%CI 1.17-1.57],每天午睡者为 1.28[1.15-1.44])。在午睡者和空腹血糖受损者之间也发现了类似的关联。排除潜在不健康和日间嗜睡的参与者并不会改变观察到的关联。

结论

在这个中国老年人样本中,午睡与糖尿病和空腹血糖受损的患病率升高有关。我们的研究结果表明,糖尿病不太可能导致日间嗜睡。这增加了午睡可能会增加患糖尿病风险的可能性。需要通过纵向研究来证实这一发现。

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