Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA.
Anal Chem. 2009 Aug 15;81(16):7091-5. doi: 10.1021/ac901071p.
This technical note describes a detailed study on wax printing, a simple and inexpensive method for fabricating microfluidic devices in paper using a commercially available printer and hot plate. The printer prints patterns of solid wax on the surface of the paper, and the hot plate melts the wax so that it penetrates the full thickness of the paper. This process creates complete hydrophobic barriers in paper that define hydrophilic channels, fluid reservoirs, and reaction zones. The design of each device was based on a simple equation that accounts for the spreading of molten wax in paper.
本技术说明详细介绍了蜡印技术，这是一种使用市售打印机和热平板在纸上制造微流控器件的简单、经济的方法。打印机将固体蜡图案打印在纸的表面，而热平板则将蜡融化，使其渗透到纸的全厚度。该过程在纸中形成完全疏水的屏障，从而定义亲水性通道、流体储液器和反应区。每个设备的设计都基于一个简单的方程式，该方程式考虑了熔融蜡在纸中的扩散。
