楝科植物川楝素和三萜。

Limonoids and triterpenoids from the stem bark of Melia toosendan.

机构信息

State Key Laboratory of Drug Research & Natural Products Chemistry Department, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu-Chong-Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, People's Republic of China.

出版信息

J Nat Prod. 2010 Apr 23;73(4):664-8. doi: 10.1021/np900835k.

DOI:10.1021/np900835k

PMID:20337487

Abstract

Four new limonoids (1, 3, 4, 6), named meliatoosenins A-D, eight new euphane- and tirucallane-type triterpenoids (8-15), named meliasenins A-H, and 13 known compounds have been isolated from the stem bark of Melia toosendan. The structures of new compounds were established on the basis of 1D and 2D NMR experiments ((1)H-(1)H COSY, HSQC, HMBC, and ROESY).

摘要

从苦楝树的茎皮中分离得到了四个新的柠檬苦素（1、3、4、6），分别命名为苦楝素 A-D，八个新的 euphane 和 tirucallane 型三萜（8-15），分别命名为苦楝素 A-H，以及 13 个已知化合物。新化合物的结构是基于 1D 和 2D NMR 实验（1H-1H COSY、HSQC、HMBC 和 ROESY）建立的。