Department of Gastroenterology, Guys' and St. Thomas' Hospitals, London, UK.
Int J Clin Pract. 2010 Jun;64(7):868-74. doi: 10.1111/j.1742-1241.2009.02267.x. Epub 2010 Mar 10.
Upper gastrointestinal (UGI) haemorrhage is a frequent cause of hospital admission. Scoring systems have been devised to identify those at risk of adverse outcomes. We evaluated the Glasgow Blatchford score's (GBS) ability to identify the need for clinical and endoscopic intervention in patients with UGI haemorrhage.
A retrospective observational study was performed in all patients who attended the A&E department with UGI haemorrhage during a 12-month period. Patients were separated into low and high risk categories. High risk encompassed patients who required blood transfusions, operative or endoscopic interventions, management on high dependency or intensive care units, and those who re-bled, represented with further bleeding, or who died.
A total of 174 patients were seen with UGI bleeding. Eight of them self-discharged and were excluded. Of the remaining 166, 94 had a 'low risk' bleed, and 72 'high risk'. The GBS was significantly higher in the high risk (median = 10) than in the low risk group (median 1, p < 0.001). To assess the validity of the GBS at separating low and high risk groups, receiver-operator characteristic (ROC) curves were plotted. The GBS had an area under ROC curve of 0.96 (95% CI 0.95-1.00). When a cut-off value of > or = 3 was used, sensitivity and specificity of GBS for identifying high risk bleeds was 100% and 68%. Thus at a cut-off value of < or = 2 the GBS is useful for distinguishing those patients with a low risk UGI bleed.
The GBS accurately identifies low risk patients who could be managed safely as outpatients.
上消化道(UGI)出血是住院的常见原因。已经设计了评分系统来识别那些有不良预后风险的患者。我们评估了格拉斯哥布莱特福德评分(GBS)在识别 UGI 出血患者需要临床和内镜干预的能力。
对在 12 个月期间因 UGI 出血就诊于急诊科的所有患者进行回顾性观察性研究。患者分为低危和高危两类。高危包括需要输血、手术或内镜干预、在高依赖或重症监护病房治疗以及再次出血、再次出血或死亡的患者。
共 174 例 UGI 出血患者就诊。其中 8 例自行出院,被排除在外。在其余 166 例中,94 例为“低危”出血,72 例为“高危”出血。高危组(中位数=10)的 GBS 明显高于低危组(中位数 1,p<0.001)。为了评估 GBS 在区分低危和高危组的有效性,绘制了受试者工作特征(ROC)曲线。GBS 的 ROC 曲线下面积为 0.96(95%CI 0.95-1.00)。当截断值>或=3 时,GBS 识别高危出血的敏感性和特异性分别为 100%和 68%。因此,当截断值<或=2 时,GBS 可用于区分低危 UGI 出血患者。
GBS 准确识别低危患者,可安全地作为门诊患者进行管理。