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头顶光疗在新生儿黄疸治疗中优于底部发光二极管光疗:一项对比研究。

Overhead is superior to underneath light-emitting diode phototherapy in the treatment of neonatal jaundice: a comparative study.

作者信息

Tayman Cuneyt, Tatli Mustafa Mansur, Aydemir Salih, Karadag Ahmet

机构信息

Department of Neonatology, Fatih University School of Medicine, Y. Ayranci, Ankara, Turkey.

出版信息

J Paediatr Child Health. 2010 May;46(5):234-7. doi: 10.1111/j.1440-1754.2009.01676.x. Epub 2010 Mar 22.

Abstract

AIM

To compare the efficacy of overhead and underneath light-emitting diode (LED) devices in the treatment of neonatal jaundice.

METHODS

We compared two LED phototherapy devices: the neoBLUE device, which provides overhead illumination, and the neoBLUE cozy device, which provides illumination from underneath the infant. The models we used had similar LED sources and provided similar light intensities (30 microW/cm(2)/nm). Infants with hyperbilirubinemia were assigned to one of two groups according to the phototherapy device used (group 1, overhead illumination, 181 infants; group 2, underneath illumination, 61 infants). Recorded variables included birthweight, gender, family history, aetiology of jaundice, total duration of phototherapy and total serum bilirubin (TSB) concentration at the initiation of phototherapy, at 12-hour intervals and just before the cessation of phototherapy. The rates of decrease in TSB concentration were calculated.

RESULTS

There were significant differences in the mean duration of phototherapy and in the rate of decrease in TSB concentration between the two groups. The mean duration of phototherapy in group 2 was higher than in group 1 (P= 0.037). The rate of decrease in TSB in group 1 was higher than in group 2 (P= 0.01).

CONCLUSION

These results suggest that when phototherapy is used in the treatment of neonatal jaundice, the direction from which the light is applied should be considered in addition to light source intensity.

摘要

目的

比较头顶式和床底式发光二极管(LED)设备治疗新生儿黄疸的疗效。

方法

我们比较了两种LED光疗设备:提供头顶照明的neoBLUE设备和从婴儿床底提供照明的neoBLUE cozy设备。我们使用的型号具有相似的LED光源,并提供相似的光强度(30微瓦/平方厘米/纳米)。根据所使用的光疗设备,将高胆红素血症婴儿分为两组之一(第1组,头顶照明,181名婴儿;第2组,床底照明,61名婴儿)。记录的变量包括出生体重、性别、家族史、黄疸病因、光疗总时长以及光疗开始时、每隔12小时和光疗即将结束前的总血清胆红素(TSB)浓度。计算TSB浓度的下降率。

结果

两组之间的光疗平均时长和TSB浓度下降率存在显著差异。第2组的光疗平均时长高于第1组(P = 0.037)。第1组的TSB下降率高于第2组(P = 0.01)。

结论

这些结果表明,在使用光疗治疗新生儿黄疸时,除了光源强度外,还应考虑光照的方向。

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