Kobayashi O, Igarashi K, Sekiya M, Saito H
Department of Internal Medicine, Niigata Prefectural Central Hospital, Joetsu, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1991 Feb;29(2):269-75.
A 52-year-old woman was admitted to our hospital because of anemia and abnormal lung shadow. She had Raynaud's symptom for 6 months, and recently developed cough and easy fatigability. She had thrombocytopenia, restrictive pulmonary dysfunction, and swollen fingers. ANF was positive (X1280), and anti-RNP antibody was also positive. Mixed connective tissue disease was diagnosed. Chest X-ray showed a diffuse alveolar pattern, and BAL revealed many hemosiderin-laden macrophages. Alveolar hemorrhage was suspected. The pulmonary shadow resolved spontaneously, and no recurrence occurred after steroid and immunosuppressant therapy.
一名52岁女性因贫血和肺部阴影异常入住我院。她有雷诺氏症状6个月，近期出现咳嗽和易疲劳。她有血小板减少、限制性肺功能障碍和手指肿胀。抗核抗体阳性（X1280），抗RNP抗体也呈阳性。诊断为混合性结缔组织病。胸部X线显示弥漫性肺泡型，支气管肺泡灌洗显示许多含铁血黄素巨噬细胞。怀疑有肺泡出血。肺部阴影自行消退，类固醇和免疫抑制剂治疗后未复发。
