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[一例与混合性结缔组织病相关的肺泡出血]

[A case of alveolar hemorrhage associated with mixed connective tissue disease].

作者信息

Kobayashi O, Igarashi K, Sekiya M, Saito H

机构信息

Department of Internal Medicine, Niigata Prefectural Central Hospital, Joetsu, Japan.

出版信息

Nihon Kyobu Shikkan Gakkai Zasshi. 1991 Feb;29(2):269-75.

PMID:2033901
Abstract

A 52-year-old woman was admitted to our hospital because of anemia and abnormal lung shadow. She had Raynaud's symptom for 6 months, and recently developed cough and easy fatigability. She had thrombocytopenia, restrictive pulmonary dysfunction, and swollen fingers. ANF was positive (X1280), and anti-RNP antibody was also positive. Mixed connective tissue disease was diagnosed. Chest X-ray showed a diffuse alveolar pattern, and BAL revealed many hemosiderin-laden macrophages. Alveolar hemorrhage was suspected. The pulmonary shadow resolved spontaneously, and no recurrence occurred after steroid and immunosuppressant therapy.

摘要

一名52岁女性因贫血和肺部阴影异常入住我院。她有雷诺氏症状6个月,近期出现咳嗽和易疲劳。她有血小板减少、限制性肺功能障碍和手指肿胀。抗核抗体阳性(X1280),抗RNP抗体也呈阳性。诊断为混合性结缔组织病。胸部X线显示弥漫性肺泡型,支气管肺泡灌洗显示许多含铁血黄素巨噬细胞。怀疑有肺泡出血。肺部阴影自行消退,类固醇和免疫抑制剂治疗后未复发。

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