Giuliari Gianpaolo, Hinkle David M, Foster C Stephen
Massachusetts Eye Research and Surgery Institution, Cambridge, MA 02142, USA.
J Ophthalmol. 2009;2009:567693. doi: 10.1155/2009/567693. Epub 2010 Feb 8.
Objective. To describe the diverse patterns observed with the use of autofluorescence fundus photography (FAF) in patients with Birdshot chorioretinopathy (BSCR). Methods. A chart review of patients with BSCR seen at the Massachusetts Eye Research and Surgery Institution, who had autofluorescence fundus photography. The data obtained included age, gender, presence of the HLA-A29 haplotype, and current treatment. Results. Eighteen eyes with HLA-A29 associated BSCR were included. Four eyes presented with active inflammation. Correspondence of the lesions noted in the colour fundus photograph was observed in 3 eyes which were more easily identified with the FAF. Fifteen eyes had fundus lesions more numerous and evident in the FAF than in the colour fundus photograph. Conclusion. Because FAF testing provides valuable insight into the metabolic state of the PR/RPE-complex, it may serve as a useful noninvasive assessment tool in patients with posterior uveitis in which the outer retina-RPE-choriocapillaries-complex is involved.
目的。描述在鸟枪弹样脉络膜视网膜病变（BSCR）患者中使用自发荧光眼底摄影（FAF）观察到的不同模式。方法。对在马萨诸塞州眼研究与手术机构就诊的接受过自发荧光眼底摄影的BSCR患者进行病历回顾。获得的数据包括年龄、性别、HLA - A29单倍型的存在情况以及当前治疗。结果。纳入18只与HLA - A29相关的BSCR眼睛。4只眼睛出现活动性炎症。在3只眼睛中观察到彩色眼底照片中记录的病变与FAF中更容易识别的病变相对应。15只眼睛的眼底病变在FAF中比在彩色眼底照片中更多且更明显。结论。由于FAF检测能为光感受器/视网膜色素上皮复合体的代谢状态提供有价值的见解，它可作为一种有用的非侵入性评估工具，用于患有涉及外层视网膜 - 视网膜色素上皮 - 脉络膜毛细血管复合体的后葡萄膜炎患者。
