Lapeyronie Hospital, 34295 CHRU Montpellier, France.
Rheumatol Int. 2010 Jul;30(9):1143-50. doi: 10.1007/s00296-010-1369-6. Epub 2010 Mar 26.
The objective of the study was to determine the current evidence to support guidelines for aerobic exercise (AE) and fibromyalgia (FM) in practice, and to outline specific research needs in these areas. Data sources consisted of a PubMed search, 2007 Cochrane Data Base Systematic review, 2008 Ottawa panel evidence-based clinical practice guidelines, as well as additional references found from the initial search. Study selection included randomized clinical trials that compared an aerobic-only exercise intervention (land or pool based) with an untreated control, a non-exercise intervention or other exercise programs in patients responding to the 1990 American College of Rheumatology criteria for FM. The following outcome data were obtained: pain, tender points, perceived improvement in FM symptoms such as the Fibromyalgia Impact Questionnaire total score (FIQ), physical function, depression (e.g., Beck Depression Inventory, FIQ subscale for depression), fatigue and sleep were extracted from 19 clinical trials that considered the effects of aerobic-only exercise in FM patients. Data synthesis shows that there is moderate evidence of important benefit of aerobic-only exercise in FM on physical function and possibly on tender points and pain. It appears to be sufficient evidence to support the practice of AE as a part of the multidisciplinary management of FM. However, future studies must be more adequately sized, homogeneously assessed, and monitored for adherence, to draw definitive conclusions.
本研究旨在确定目前有哪些循证医学证据支持在实践中应用有氧运动(AE)和纤维肌痛(FM)的指南,并概述这些领域的具体研究需求。数据来源包括 PubMed 检索、2007 年 Cochrane 数据库系统评价、2008 年渥太华小组循证临床实践指南,以及从初始检索中找到的其他参考文献。研究选择包括比较单纯有氧运动干预(陆地或泳池)与未治疗对照组、非运动干预或其他运动方案在符合 1990 年美国风湿病学会纤维肌痛标准的患者中的随机临床试验。从考虑单纯有氧运动对 FM 患者影响的 19 项临床试验中提取了以下结局数据:疼痛、压痛点、FM 症状(如纤维肌痛影响问卷总评分(FIQ))、身体功能、抑郁(如贝克抑郁量表、FIQ 抑郁分量表)、疲劳和睡眠的改善情况。数据综合表明,有中等质量的证据表明,FM 患者单纯进行有氧运动对身体功能,可能对压痛点和疼痛有重要益处。这似乎足以支持将 AE 作为 FM 多学科管理的一部分进行实践。然而,未来的研究必须在规模、评估方法和依从性监测方面更加充分,以得出明确的结论。