Escola Paulista de Medicina, Diabetes Center, Federal University of São Paulo, São Paulo, Brazil.
Diabetol Metab Syndr. 2010 Mar 26;2:21. doi: 10.1186/1758-5996-2-21.
The adipose tissue is an endocrine organ producing substances called adipocytokines that have different effects on lipid metabolism, metabolic syndrome, and cardiovascular risk. Visfatin was recently described as an adipocytokine with potentially important effects on glucose metabolism and atherosclerosis. Visfatin has been linked to several inflammatory conditions, beta cell function, and cardiovascular disease. The growing number of publications on the subject shall bring further evidence about this adipocytokine. Its findings may contribute in the identification of higher risk individuals for diabetes and cardiovascular disease with a better comprehension about the complex intercorrelation between adiposity, glucose metabolism and vascular disease.
脂肪组织是一种内分泌器官，可产生称为脂肪细胞因子的物质，这些物质对脂代谢、代谢综合征和心血管风险具有不同的影响。内脂素最近被描述为一种具有潜在重要作用的脂肪细胞因子，可影响葡萄糖代谢和动脉粥样硬化。内脂素与几种炎症状态、β细胞功能和心血管疾病有关。关于该脂肪细胞因子的研究文献日益增多，将提供更多证据。其研究结果可能有助于确定糖尿病和心血管疾病风险较高的个体，并更好地理解肥胖、葡萄糖代谢和血管疾病之间的复杂相互关系。
