The Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.
Ophthalmology. 2010 Jul;117(7):1423-9.e2. doi: 10.1016/j.ophtha.2009.11.028. Epub 2010 Mar 27.
To improve understanding of vision loss and clinical findings, we studied gross and microscopic pathology of retinas and optic nerves of individuals with Terson's syndrome.
Retrospective case series with clinicopathologic correlation.
We included 109 deceased individuals with Terson's syndrome.
Histologic sections and gross photographs from 109 cases of Terson's Syndrome, accessed from 1955 to 1992 at the Wm R. Green Laboratory of Ocular Pathology, were studied and photographed; a representative case is described in detail.
Abnormalities in retina and optic nerve.
Hemorrhages occur in vitreous, subhyaloid, sub-internal limiting membrane (ILM), intraretinal, and subretinal spaces, in association with macular holes, retinal detachments, and optic neuropathy. Subhyaloid hemorrhages have diffuse morphology, whereas sub-ILM are well-demarcated. Continuous and noncontinuous blood occurs along optic nerves, within nerve sheaths, and in the subdural and subarachnoid spaces.
Blood occurring in various layers and locations of the retina, particularly the macula, causes various complications that influence clinical management and visual outcome. Morphology differentiates subhyaloid from sub-ILM hemorrhage. Patterns of hemorrhages of optic nerve contribute to understanding mechanisms of Terson's syndrome.
FINANCIAL DISCLOSURE(S): The authors have no proprietary or commercial interest in any of the materials discussed in this article.
为了提高对视力丧失和临床发现的理解，我们研究了 Terson 综合征患者的视网膜和视神经的大体和显微镜病理学。
具有临床病理相关性的回顾性病例系列。
我们纳入了 109 例 Terson 综合征患者。
从 1955 年至 1992 年，在 Wm R. Green 眼病理实验室获得了 109 例 Terson 综合征的组织学切片和大体照片，并对其进行了研究和拍摄；详细描述了一个有代表性的病例。
视网膜和视神经异常。
玻璃体内、玻璃下、内界膜下（ILM）、视网膜内和视网膜下间隙出现出血，伴有黄斑裂孔、视网膜脱离和视神经病变。玻璃下出血呈弥漫性形态，而 ILM 下出血边界清晰。视神经、神经鞘内以及硬脑膜下和蛛网膜下间隙内可见连续和非连续的血液。
血液出现在视网膜的不同层和位置，特别是黄斑区，引起各种并发症，影响临床管理和视力预后。玻璃下和 ILM 下出血的形态学有助于区分两者。视神经出血模式有助于理解 Terson 综合征的发病机制。
作者对本文讨论的任何材料均无专有或商业利益。
