Department of Psychiatry & Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, United States.
Contemp Clin Trials. 2010 Jul;31(4):312-22. doi: 10.1016/j.cct.2010.03.009. Epub 2010 Mar 27.
Diabetes and coronary heart disease (CHD) are two of the most prevalent medical illnesses in the US population and comorbid depression occurs in up to 20% of these patients. Guidelines for management of diabetes and CHD overlap for healthy lifestyle and disease-control recommendations. However, the majority of patients with these medical illnesses have been shown to have inadequate control of key risk factors such as blood pressure, LDL cholesterol, or blood sugar. Comorbid depression has been shown to adversely affect self-care of diabetes and CHD, and is associated with an increased risk of complications and mortality. Interventions that have improved quality and outcomes of depression care alone in patients with diabetes and CHD have not demonstrated benefits in self-care, improved disease control or morbidity and mortality. This paper describes the design and development of a new biopsychosocial intervention (TEAMcare) aimed at improving both medical disease control and depression in patients with poor control of diabetes and/or CHD who met the criteria for comorbid depression. A team approach is used with a nurse interventionist who receives weekly psychiatric and primary care physician caseload supervision in order to enhance treatment by the primary care physician. This intervention is being tested in an NIMH-funded randomized controlled trial in a large integrated health plan.
糖尿病和冠心病(CHD)是美国人群中最常见的两种医学疾病,高达 20%的这些患者同时患有抑郁症。糖尿病和 CHD 的管理指南在健康生活方式和疾病控制建议方面存在重叠。然而,大多数患有这些医学疾病的患者的关键风险因素(如血压、LDL 胆固醇或血糖)控制不足。同时患有抑郁症已被证明会对糖尿病和 CHD 的自我护理产生不利影响,并与并发症和死亡率增加相关。单独改善糖尿病和 CHD 患者的抑郁护理质量和结果的干预措施并未显示在自我护理、改善疾病控制或发病率和死亡率方面有获益。本文描述了一种新的生物心理社会干预(TEAMcare)的设计和开发,旨在改善糖尿病和/或 CHD 控制不良且符合合并抑郁症标准的患者的医学疾病控制和抑郁状况。采用团队方法,由一名护士干预者负责,每周接受精神病学和初级保健医生的病例量监督,以增强初级保健医生的治疗效果。这项干预措施正在一项由 NIMH 资助的、在大型综合医疗计划中进行的随机对照试验中进行测试。