Department of Ophthalmology, Federal University of São Paulo, Rua Botucatu, 821, São Paulo-SP 04023-062, Brazil.
Acupunct Med. 2010 Mar;28(1):25-7. doi: 10.1136/aim.2009.001081.
To evaluate the short-term effect of acupuncture on the intraocular pressure (IOP) in healthy subjects.
A randomised controlled double-blinded trial was performed. 48 healthy volunteers (94 eyes) were randomly allocated to three groups: acupuncture group-19 subjects (38 eyes) were submitted to a 20 min session of acupuncture (GB1, GB14 and BL1); sham group-14 subjects (27 eyes) were submitted to a 20 min session of acupuncture with needles inserted in false points; and control group-15 subjects (29 eyes) who underwent no intervention. All subjects had the IOP measured by a masked investigator using Goldmann applanation tonometry immediately before intervention, as well as 20 min and 24 h after.
The mean (SD) IOP in the acupuncture group was 17.9 (3.3) mm Hg at baseline, 16.4 (3.9) mm Hg at 20 min and 16.3 (3.3) mm Hg at 24 h. The mean (SD) IOP in the sham group was 18.6 (3.3) mm Hg at baseline, 17.7 (2.6) mm Hg at 20 min and 15.9 (3.6) mm Hg at 24 h. The mean (SD) IOP in the control group was 16.9 (3.5) mm Hg at baseline, 16.5 (3.8) mm Hg at 20 min and 15.8 (3.3) mm Hg at 24 h. There was no statistically significant difference in the IOP variation (post-intervention minus baseline measurements) between groups after 20 min (p=0.13) and 24 h (p=0.21).
Acupuncture in the studied points did not produce significant short-term effect on the IOP of healthy individuals in comparison with control groups.
评估针刺对健康受试者眼内压（IOP）的短期影响。
进行了一项随机对照双盲试验。将 48 名健康志愿者（94 只眼）随机分为三组：针刺组-19 名受试者（38 只眼）接受 20 分钟的针刺（GB1、GB14 和 BL1）；假针刺组-14 名受试者（27 只眼）接受 20 分钟的假针刺，针插入假穴位；对照组-15 名受试者（29 只眼）不接受干预。所有受试者均由一名经过盲法培训的研究者使用 Goldmann 压平眼压计在干预前、干预后 20 分钟和 24 小时测量眼压。
针刺组的平均（标准差）眼压在基线时为 17.9（3.3）mmHg，在 20 分钟时为 16.4（3.9）mmHg，在 24 小时时为 16.3（3.3）mmHg。假针刺组的平均（标准差）眼压在基线时为 18.6（3.3）mmHg，在 20 分钟时为 17.7（2.6）mmHg，在 24 小时时为 15.9（3.6）mmHg。对照组的平均（标准差）眼压在基线时为 16.9（3.5）mmHg，在 20 分钟时为 16.5（3.8）mmHg，在 24 小时时为 15.8（3.3）mmHg。在 20 分钟（p=0.13）和 24 小时（p=0.21）时，三组之间的眼压变化（干预后与基线测量值的差值）无统计学差异。
与对照组相比，针刺研究穴位对健康个体的眼压没有产生显著的短期影响。
