Department of Plant Pathology and Microbiology, Texas A&M University, 202 Horticultural and Forestry Sciences Building, College Station, TX 77843-2133, USA.
Appl Microbiol Biotechnol. 2010 May;86(6):1659-70. doi: 10.1007/s00253-010-2509-3. Epub 2010 Mar 30.
Phenazines constitute a large group of nitrogen-containing heterocyclic compounds produced by a diverse range of bacteria. Both natural and synthetic phenazine derivatives are studied due their impacts on bacterial interactions and biotechnological processes. Phenazines serve as electron shuttles to alternate terminal acceptors, modify cellular redox states, act as cell signals that regulate patterns of gene expression, contribute to biofilm formation and architecture, and enhance bacterial survival. Phenazines have diverse effects on eukaryotic hosts and host tissues, including the modification of multiple host cellular responses. In plants, phenazines also may influence growth and elicit induced systemic resistance. Here, we discuss emerging evidence that phenazines play multiple roles for the producing organism and contribute to their behavior and ecological fitness.
吩嗪类化合物是由多种细菌产生的一大类含氮杂环化合物。天然和合成的吩嗪衍生物都因其对细菌相互作用和生物技术过程的影响而受到研究。吩嗪类化合物作为电子穿梭体，可替代末端受体，改变细胞氧化还原状态，作为调节基因表达模式的细胞信号，有助于生物膜的形成和结构，并增强细菌的生存能力。吩嗪类化合物对真核宿主和宿主组织有多种影响，包括改变多种宿主细胞反应。在植物中，吩嗪类化合物也可能影响生长并引发系统诱导抗性。在这里，我们讨论了新出现的证据，表明吩嗪类化合物对产生它们的生物体起着多种作用，并有助于它们的行为和生态适应性。
