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一种用于极低场开放获取的人体肺部成像系统。

A System for Open-Access He Human Lung Imaging at Very Low Field.

作者信息

Ruset I C, Tsai L L, Mair R W, Patz S, Hrovat M I, Rosen M S, Muradian I, Ng J, Topulos G P, Butler J P, Walsworth R L, Hersman F W

机构信息

Department of Physics, University of New Hampshire, Physics Department, 9 Library Way, DeMeritt Hall, Durham, New Hampshire 03824.

出版信息

Concepts Magn Reson Part B Magn Reson Eng. 2006;29(4):210-221. doi: 10.1002/cmr.b.20075.

Abstract

We describe a prototype system built to allow open-access very-low-field MRI of human lungs using laser-polarized (3)He gas. The system employs an open four-coil electromagnet with an operational B(0) field of 4 mT, and planar gradient coils that generate gradient fields up to 0.18 G/cm in the x and y direction and 0.41 G/cm in the z direction. This system was used to obtain (1)H and (3)He phantom images and supine and upright (3)He images of human lungs. We include discussion on challenges unique to imaging at 50 -200 kHz, including noise filtering and compensation for narrow-bandwidth coils.

摘要

我们描述了一个构建的原型系统,该系统利用激光极化的³He气体实现人体肺部的开放式、超低场磁共振成像。该系统采用一个开放式四线圈电磁铁,其工作B₀场强为4 mT,还有平面梯度线圈,在x和y方向可产生高达0.18 G/cm的梯度场,在z方向可产生高达0.41 G/cm的梯度场。该系统用于获取¹H和³He体模图像以及人体肺部的仰卧位和直立位³He图像。我们还讨论了在50 - 200 kHz成像时所特有的挑战,包括噪声滤波和窄带宽线圈的补偿。

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本文引用的文献

1
3He lung imaging in an open access, very-low-field human magnetic resonance imaging system.
Magn Reson Med. 2005 Apr;53(4):745-9. doi: 10.1002/mrm.20456.
5
MRI of the lung using hyperpolarized 3He at very low magnetic field (3 mT).
MAGMA. 2004 May;16(6):255-8. doi: 10.1007/s10334-004-0035-y. Epub 2004 Mar 16.
6
MRI of the lung gas-space at very low-field using hyperpolarized noble gases.
Magn Reson Imaging. 2003 Sep;21(7):773-6. doi: 10.1016/s0730-725x(03)00178-4.
7
Functional magnetic resonance imaging of the lung.肺部功能磁共振成像
Br J Anaesth. 2003 Jul;91(1):16-30. doi: 10.1093/bja/aeg149.
8
Dynamic radial projection MRI of inhaled hyperpolarized 3He gas.
Magn Reson Med. 2003 Jun;49(6):991-7. doi: 10.1002/mrm.10477.

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