The Lewis B. and Dorothy Cullman Cancer Chemoprotection Center, Department of Pharmacology and Molecular Sciences, School of Medicine, Johns Hopkins University, Baltimore, Maryland 21205, USA.
Photochem Photobiol Sci. 2010 Apr;9(4):597-600. doi: 10.1039/b9pp00130a.
Feeding broccoli sprout extracts providing daily doses of 10 micromol of glucoraphanin to SKH-1 hairless mice with prior chronic exposure to UV radiation (30 mJ cm(-2) of UVB, twice a week, for 17 weeks) inhibited the development of skin tumors during the subsequent 13 weeks; compared to the controls, tumor incidence, multiplicity, and volume were reduced by 25, 47, and 70%, respectively, in the animals that received the protective agent.
给先前经慢性紫外线辐射（每周两次，共 17 周，每次 30mJ/cm² 的 UVB）处理的 SKH-1 无毛小鼠喂食西兰花芽提取物，其每日剂量为 10 微摩尔萝卜硫苷，可在随后的 13 周内抑制皮肤肿瘤的发展；与对照组相比，接受保护剂的动物的肿瘤发生率、多发性和体积分别降低了 25%、47%和 70%。
