Lopata Christopher, Toomey Jennifer A, Fox Jeffery D, Volker Martin A, Chow Sabrina Y, Thomeer Marcus L, Lee Gloria K, Rodgers Jonathan D, McDonald Christin A, Smerbeck Audrey M
Institute for Autism Research, Health Sciences 216, Canisius College, 2001 Main Street, Buffalo, NY 14208-1098, USA.
J Abnorm Child Psychol. 2010 Aug;38(6):765-76. doi: 10.1007/s10802-010-9406-1.
The purpose of this study was to: (1) examine symptom levels of anxiety and depression in children with high-functioning autism spectrum disorders (HFASDs) compared with matched control children using child self-reports and parent ratings; and (2) examine source differences within the two condition groups. An overall multivariate effect indicated significantly elevated depression and anxiety symptoms for children with HFASDs based on parent reports; however no significant between-group differences based on child self-reports. Within-condition source comparisons (parent vs. child) revealed a significant multivariate effect indicating a significant difference in symptoms of depression and anxiety for the HFASD group but none for the control. Correlations between parent and child reports for the HFASD group suggested some positive association between child-reports and parent-reports for depressive symptoms only; however, the difference in average scores reflected a substantial discrepancy in the magnitude of symptoms by rater. Implications for clinical assessment and future research are provided.
（1）与匹配的对照儿童相比，使用儿童自我报告和家长评分，检查高功能自闭症谱系障碍（HFASD）儿童的焦虑和抑郁症状水平；（2）检查两个条件组内的来源差异。总体多变量效应表明，根据家长报告，HFASD儿童的抑郁和焦虑症状显著升高；然而，根据儿童自我报告，组间无显著差异。条件内来源比较（家长与儿童）显示出显著的多变量效应，表明HFASD组在抑郁和焦虑症状方面存在显著差异，而对照组则无差异。HFASD组家长报告与儿童报告之间的相关性表明，仅在抑郁症状方面，儿童报告与家长报告之间存在一些正相关；然而，平均得分的差异反映了评分者在症状严重程度上的实质性差异。本研究还提供了对临床评估和未来研究的启示。
