Gastroenterology and Endoscopy Unit, Ospedale San Giuseppe, Via dell'Olivella, Albano Laziale, Rome 00041, Italy.
World J Gastroenterol. 2010 Apr 7;16(13):1665-9. doi: 10.3748/wjg.v16.i13.1665.
Gastrointestinal perforations are conservatively managed at endoscopy by through-the-scope endoclips and covered self expandable stents, according to the size and tissue features of the perforation. This is believed to be the first report of successful closure of two gastro-cutaneous fistulas with over-the-scope clips (OTSCs). After laparoscopic gastric banding, a 45-year old woman presented with band erosion and penetration. Despite surgical band removal and gastric wall suturing, external drainage of enteric material persisted for 2 wk, and esophagogastroduodenoscopy demonstrated two adjacent 10-mm and 15-mm fistulous orifices at the esophagogastric junction. After cauterization of the margins, the 10-mm fistulous tract was grasped by the OTSC anchor, invaginated into the applicator cap, and closed by a traumatic OTSC. The other 15-mm fistula was too large to be firmly grasped, and a fully-covered metal stent was temporarily placed. No leak occurred during the following 6 wk. At stent removal: the OTSC was completely embedded in hyperplastic overgrowth; the 15-mm fistula significantly reduced in diameter, and it was closed by another traumatic OTSC. After the procedure, no external fistula recurred and both OTSCs were lost spontaneously after 4 wk. The use of the anchor and the OTSC seem highly effective for successful closure of small chronic perforations.
胃肠道穿孔可通过内镜下经腔内夹闭和覆盖自膨式支架进行保守治疗,具体取决于穿孔的大小和组织特征。这被认为是首例使用过内镜下全覆膜带结扎夹(OTSC)成功闭合两个胃肠皮肤瘘的报道。腹腔镜胃束带术后,一名 45 岁女性出现束带侵蚀和穿透。尽管进行了手术束带去除和胃壁缝合,但肠内容物仍持续外引流 2 周,食管胃十二指肠镜检查显示食管胃交界处有两个相邻的 10mm 和 15mm 的瘘口。边缘烧灼后,OTSC 锚抓住 10mm 的瘘管,向内翻入施夹器帽,并通过创伤性 OTSC 闭合。另一个 15mm 的瘘口太大,无法牢固抓住,因此暂时放置了一个全覆膜金属支架。在接下来的 6 周内没有发生漏液。在取出支架时:OTSC 完全嵌入增生性过度生长中;15mm 的瘘口显著缩小,并通过另一个创伤性 OTSC 闭合。该操作后,无外部瘘复发,并且在 4 周后两个 OTSC 均自行丢失。锚和 OTSC 的使用对于成功闭合小的慢性穿孔似乎非常有效。