Department of Surgery, German Clinic of Santiago, Santiago, Chile.
Obes Surg. 2010 Jun;20(6):744-8. doi: 10.1007/s11695-010-0136-9.
The different bariatric surgery techniques that alter the digestive anatomy also modify the gastric absorption surface. Since alcohol is a substance that is mainly metabolized in the stomach, the goal of this study was to determine alcohol absorption before and after a laparoscopic sleeve gastrectomy (LSG) in the same patients.
Studies were carried out on 12 morbidly obese patients who underwent a LSG (eight men and four women). Each patient was given 3.6 ml of red wine to drink at 14% for each liter of body water mass. Alcotest values (Alcoscan Alcomate AL-6000) were measured 10 min after the wine dose had been consumed. Measurements were then repeated every 5 min until the alcohol had been completely eliminated from the bloodstream. During the postoperatory period (median of 2.3 months), the measurement was repeated with the total dose per kg adjusted to the new water body mass. The results were measured with a nonparametric analysis for repeated samples.
The maximum average peak of the Alcotest was 2.02 g/l during the postoperative period compared to 0.87 g/l during the preoperative period (p = 0.001 Wilcoxon). At 175 min, the blood alcohol level value reaches zero (0) in all pre-operatory patients, while after surgery, an average value of 0.26 g/l was observed (p = 0.027 Wilcoxon). After 4 h, an Alcotest average of 0.20 g/l was observed in these patients.
Alcohol absorption was considerably modified after LSG with higher and longer blood alcohol values for equivalent amounts of alcohol.
改变消化道解剖结构的不同减重手术技术也会改变胃吸收面积。由于酒精主要在胃中代谢，本研究的目的是在同一批患者中确定腹腔镜袖状胃切除术（LSG）前后的酒精吸收情况。
对 12 名接受 LSG（8 名男性和 4 名女性）的病态肥胖患者进行了研究。每位患者都被给予 3.6 毫升 14%的红酒，每升体水质量为 1 毫升。在饮酒后 10 分钟测量 Alcotest 值（Alcoscan Alcomate AL-6000）。然后，每 5 分钟重复测量一次，直到酒精从血液中完全消除。在术后期间（中位数为 2.3 个月），根据新的体水质量调整每公斤的总剂量重复测量。使用非参数分析对重复样本进行了测量。
术后平均最大酒精峰值为 2.02g/L，而术前为 0.87g/L（p=0.001Wilcoxon）。在 175 分钟时，所有术前患者的血液酒精水平值均为零（0），而手术后，观察到平均 0.26g/L（p=0.027Wilcoxon）。4 小时后，这些患者的平均 Alcotest 值为 0.20g/L。
LSG 后酒精吸收明显改变，相同酒精量的血液酒精水平更高、持续时间更长。
