• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

评估仅用水对油基制剂进行去污所需的时间。

Evaluation of time required for water-only decontamination of an oil-based agent.

作者信息

Moffett Peter M, Baker Benjamin L, Kang Christopher S, Johnson Melinda S

机构信息

Madigan Army Medical Center, ATTN MCHJ-EM, Tacoma, WA 98431, USA.

出版信息

Mil Med. 2010 Mar;175(3):185-7. doi: 10.7205/milmed-d-09-00012.

DOI:10.7205/milmed-d-09-00012
PMID:20358708
Abstract

STUDY OBJECTIVE

The objective was to evaluate the time to decontaminate an area of skin exposed to an oil-based agent using a water-only decontamination protocol.

METHODS

A fluorescent mock chemical/biological agent was created. Each of 20 subjects had his/her forearm sprayed with the agent. Each subject placed his/her arm under a decontamination shower, which provided water at a pressure of 60-70 psi and 35 degrees C. After 30 sec a black light was used by three evaluators to determine whether the agent was removed. The process of 30 sec decontamination and re-evaluation was repeated for a total of 5 min. The primary endpoint was proportion decontaminated over time.

RESULTS

After 90 sec, 100% of subjects were decontaminated.

CONCLUSION

Whereas the data suggest the possibility of rapid water-only decontamination, the applicability of this data in current form is doubtful, but provides a model as a basis for future study.

摘要

研究目的

目的是评估使用仅用水的去污方案对暴露于油基制剂的皮肤区域进行去污所需的时间。

方法

创建了一种荧光模拟化学/生物制剂。20名受试者的每人均在其前臂喷洒该制剂。每名受试者将其手臂置于去污淋浴喷头下,该喷头提供压力为60 - 70磅力/平方英寸且温度为35摄氏度的水。30秒后,三名评估人员使用黑光来确定制剂是否已被去除。30秒去污和重新评估的过程重复进行,总共持续5分钟。主要终点是随时间推移已去污的比例。

结果

90秒后,100%的受试者已被去污。

结论

尽管数据表明仅用水快速去污是有可能的,但以当前形式呈现的数据的适用性存疑,但可为未来研究提供一个模型基础。

相似文献

1
Evaluation of time required for water-only decontamination of an oil-based agent.评估仅用水对油基制剂进行去污所需的时间。
Mil Med. 2010 Mar;175(3):185-7. doi: 10.7205/milmed-d-09-00012.
2
Efficacy studies of Reactive Skin Decontamination Lotion, M291 Skin Decontamination Kit, 0.5% bleach, 1% soapy water, and Skin Exposure Reduction Paste Against Chemical Warfare Agents, part 1: guinea pigs challenged with VX.反应性皮肤去污洗剂、M291皮肤去污套件、0.5%漂白剂、1%肥皂水和皮肤暴露减少膏对化学战剂的功效研究,第1部分:用VX攻击的豚鼠
Cutan Ocul Toxicol. 2011 Mar;30(1):15-28. doi: 10.3109/15569527.2010.515280. Epub 2010 Oct 13.
3
The impact of skin decontamination on the time window for effective treatment of percutaneous VX exposure.皮肤去污对经皮接触VX有效治疗时间窗的影响。
Chem Biol Interact. 2017 Apr 1;267:48-56. doi: 10.1016/j.cbi.2016.02.001. Epub 2016 Feb 5.
4
Development of haemostatic decontaminants for treatment of wounds contaminated with chemical warfare agents. 3: Evaluation of in vitro topical decontamination efficacy using damaged skin.用于治疗化学战剂污染伤口的止血去污剂的研发。3:使用受损皮肤评估体外局部去污效果。
J Appl Toxicol. 2017 Aug;37(8):976-984. doi: 10.1002/jat.3446. Epub 2017 Feb 20.
5
Development of haemostatic decontaminants for the treatment of wounds contaminated with chemical warfare agents. 2: evaluation of in vitro topical decontamination efficacy using undamaged skin.用于治疗化学战剂污染伤口的止血去污剂的研发。2:使用未受损皮肤评估体外局部去污效果。
J Appl Toxicol. 2015 May;35(5):543-50. doi: 10.1002/jat.3060. Epub 2014 Sep 12.
6
Comparison of selected skin decontaminant products and regimens against VX in domestic swine.在家猪中比较选定的皮肤去污产品和方案对VX的防护效果。
Hum Exp Toxicol. 2008 Mar;27(3):253-61. doi: 10.1177/0960327108090269.
7
Water-based solutions are the best decontaminating fluids for dermal corrosive exposures: a mini review.水基溶液是皮肤腐蚀性暴露的最佳去污流体:小型综述。
Clin Toxicol (Phila). 2013 Sep-Oct;51(8):731-6. doi: 10.3109/15563650.2013.838628. Epub 2013 Sep 5.
8
The percutaneous toxicokinetics of VX in a damaged skin porcine model and the evaluation of WoundStat™ as a topical decontaminant.VX在受损皮肤猪模型中的经皮毒代动力学及WoundStat™作为局部去污剂的评估。
J Appl Toxicol. 2018 Mar;38(3):318-328. doi: 10.1002/jat.3542. Epub 2017 Oct 10.
9
Efficacy studies of Reactive Skin Decontamination Lotion, M291 Skin Decontamination Kit, 0.5% bleach, 1% soapy water, and Skin Exposure Reduction Paste Against Chemical Warfare Agents, part 2: guinea pigs challenged with soman.反应性皮肤去污洗剂、M291皮肤去污套件、0.5%漂白剂、1%肥皂水和皮肤暴露减少膏剂对化学战剂的功效研究,第2部分:用梭曼攻击的豚鼠
Cutan Ocul Toxicol. 2011 Mar;30(1):29-37. doi: 10.3109/15569527.2010.515281. Epub 2010 Oct 21.
10
Reactive skin decontamination lotion (RSDL) for the decontamination of chemical warfare agent (CWA) dermal exposure.用于化学战剂(CWA)皮肤暴露的去污的反应性皮肤去污洗剂(RSDL)。
Curr Pharm Biotechnol. 2012 Aug;13(10):1971-9. doi: 10.2174/138920112802273191.

引用本文的文献

1
Impact of Skin Decontamination Wipe Solutions on the Percutaneous Absorption of Polycyclic Aromatic Hydrocarbons.皮肤去污擦拭溶液对多环芳烃经皮吸收的影响
Toxics. 2024 Sep 30;12(10):716. doi: 10.3390/toxics12100716.
2
Mass Casualty Decontamination for Chemical Incidents: Research Outcomes and Future Priorities.批量伤员洗消处理化学突发事件:研究结果和未来重点。
Int J Environ Res Public Health. 2021 Mar 17;18(6):3079. doi: 10.3390/ijerph18063079.
3
Evidence-based patient decontamination: an integral component of mass exposure chemical incident planning and response.
基于证据的患者去污:大规模暴露化学事故规划与应对的一个组成部分。
Disaster Med Public Health Prep. 2014 Jun;8(3):260-266. doi: 10.1017/dmp.2014.41. Epub 2014 May 27.
4
Chemical, biological, radiological, and nuclear decontamination: Recent trends and future perspective.化学、生物、放射和核去污:最新趋势与未来展望。
J Pharm Bioallied Sci. 2010 Jul;2(3):220-38. doi: 10.4103/0975-7406.68505.