用于生化分析的光纤传感器的发展研究。

Studies of the development of optical fiber sensors for biochemical analysis.

作者信息

Takai N, Sakuma I, Fukui Y, Kaneko A, Fujie T, Taguchi K, Nagaoka S

机构信息

Institute of Industrial Science, University of Tokyo, Japan.

出版信息

Artif Organs. 1991 Apr;15(2):86-9. doi: 10.1111/j.1525-1594.1991.tb00765.x.

DOI:10.1111/j.1525-1594.1991.tb00765.x

PMID:2036067

Abstract

An optical fiber sensor utilizing Thymol blue and an ion-exchange resin complex in a cellulose acetate membrane was developed. By monitoring several different chromophores of Thymol blue, the sensor could measure the pH of the solution from 1.0 to 12.0 with good reproducibility. An optical fiber glucose sensor utilizing a cellulose acetate membrane containing glucose oxidase, 2,7-diaminofluorene dihydrochloride, and sodium N-(3-sulfopropyl)-3,3',5,5'-tetramethylbenzidine was developed. Reflectance changes at 580 nm were large enough to trace changes in glucose concentration in physiological saline solution.

摘要

开发了一种利用百里酚蓝与离子交换树脂络合物并置于醋酸纤维素膜中的光纤传感器。通过监测百里酚蓝的几种不同发色团，该传感器能够在1.0至12.0的范围内测量溶液的pH值，重现性良好。还开发了一种光纤葡萄糖传感器，其利用含有葡萄糖氧化酶、2,7 - 二氨基芴二盐酸盐和N -（3 - 磺丙基）- 3,3',5,5' - 四甲基联苯胺钠的醋酸纤维素膜。在580 nm处的反射率变化足够大，能够追踪生理盐溶液中葡萄糖浓度的变化。