Volkov V S, Poseliugina O B, Nilova S A, Vinogradova T S, Rokkina S A, Svistunov O P
Klin Med (Mosk). 2010;88(1):15-8.
The study included 630 patients with verified diagnosis of arterial hypertension (AH) in whom 24 hr AP monitoring was performed, threshold gustatory sensitivity of the tongue to table salt (TGS) measured, and habit to add salt to the cooked food evaluated. Measurement of Na in daily urine of 442 patients was followed by estimation of salt consumption. The results were compared with those obtained in 100 patients with newly diagnosed AH. The control group comprised 288 subjects. TGS in AH patients was significantly higher than in controls and directly related to clinical features of the disease, high AP values, age, smoking habits, hypercholesterolemia, abdominal-type obesity, and hereditary predisposition. TGS positively correlated with daily urinary excretion of NaCl (r = 0.4-0.7; p < 0.05-0.01). High TGS decreased under effect of hypotensive therapy.
该研究纳入了630例确诊为动脉高血压（AH）的患者，对其进行了24小时动态血压监测，测量了舌对食盐的阈值味觉敏感性（TGS），并评估了在熟食中加盐的习惯。对442例患者的每日尿钠进行测量，随后估算盐摄入量。将结果与100例新诊断AH患者的结果进行比较。对照组包括288名受试者。AH患者的TGS显著高于对照组，且与疾病的临床特征、高血压值、年龄、吸烟习惯、高胆固醇血症、腹型肥胖和遗传易感性直接相关。TGS与每日尿氯化钠排泄呈正相关（r = 0.4 - 0.7；p < 0.05 - 0.01）。在降压治疗的作用下，高TGS降低。
