• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

新鲜距骨同种异体移植物治疗距骨骨软骨病变。

Osteochondral lesions of the talus treated with fresh talar allografts.

机构信息

The Denver Clinic for Extremities at Risk, Limb Preservation, 1601 E. 19th Ave., Denver, CO 80218, USA.

出版信息

Foot Ankle Int. 2010 Apr;31(4):277-82. doi: 10.3113/FAI.2010.0277.

DOI:10.3113/FAI.2010.0277
PMID:20371012
Abstract

BACKGROUND

Osteochondral lesions of the talar dome (OLT) can be devastating injuries. Many of these problems occur in younger adult patients and can cause permanent joint pain and stiffness. Several treatment methods have been used to treat the symptomatic lesion, including arthroscopic debridement and microfracture, transfer of autologous osteoarticular tissue from the knee or talus (OATS), autologous chondrocyte implantation (ACI), frozen and fresh allograft transplantation.

MATERIALS AND METHODS

Eighteen patients underwent fresh talar allograft transplantation with internal fixation for an OLT. Fresh talar allograft transplantation involved arthrotomy of the ankle, often with malleolar osteotomy, and replacement of the talar dome defect with fresh talar allograft tissue and internal fixation. Thirteen of the 18 patients returned for clinical and radiographic examination in addition to completing two validated questionnaires. The other five patients did not return for followup evaluation. The 13 patients who were seen in followup had an average age of 30 (range, 15 to 44) years with a mean followup of 48 months.

RESULTS

There was a significant difference (p < 0.01) between the patients' preoperative and postoperative pain and activity abilities as measured with the Foot Function Index and AOFAS Ankle-Hindfoot questionnaires. Clinical examination and X-rays confirmed healing of the graft.

CONCLUSION

Based on these results, we conclude that this is a reasonable procedure for younger adult patients with focal osteochondral talar defects that cannot be corrected with curettage and microfracture.

摘要

背景

距骨穹隆骨软骨损伤(OLT)可能是破坏性损伤。这些问题大多发生在年轻的成年患者中,可导致永久性关节疼痛和僵硬。已经使用了多种治疗方法来治疗有症状的病变,包括关节镜下清创术和微骨折术、从膝盖或距骨转移自体骨软骨组织(OATS)、自体软骨细胞植入术(ACI)、冷冻和新鲜同种异体移植物移植。

材料和方法

18 例 OLT 患者接受新鲜距骨同种异体移植内固定治疗。新鲜距骨同种异体移植包括踝关节关节切开术,通常伴有踝骨切开术,并使用新鲜距骨同种异体组织和内固定置换距骨穹隆缺损。18 例患者中有 13 例除完成两份有效问卷外,还接受了临床和影像学检查。另外 5 例患者未返回进行随访评估。在随访中看到的 13 例患者的平均年龄为 30 岁(范围为 15 至 44 岁),平均随访时间为 48 个月。

结果

患者术前和术后的疼痛和活动能力(通过足功能指数和 AOFAS 踝关节-后足问卷测量)有显著差异(p < 0.01)。临床检查和 X 射线证实移植物愈合。

结论

基于这些结果,我们得出结论,对于不能通过刮除和微骨折术矫正的年轻成年患者,有局灶性距骨骨软骨缺损,这是一种合理的治疗方法。

相似文献

1
Osteochondral lesions of the talus treated with fresh talar allografts.新鲜距骨同种异体移植物治疗距骨骨软骨病变。
Foot Ankle Int. 2010 Apr;31(4):277-82. doi: 10.3113/FAI.2010.0277.
2
Fresh osteochondral allografting for osteochondral lesions of the talus.新鲜骨软骨同种异体移植治疗距骨骨软骨病变。
Foot Ankle Int. 2010 Apr;31(4):283-90. doi: 10.3113/FAI.2010.0283.
3
Role of Fresh Osteochondral Allografts for Large Talar Osteochondral Lesions.新鲜骨软骨异体移植在距骨大的骨软骨损伤中的作用。
Instr Course Lect. 2016;65:301-9.
4
Intermediate outcomes of fresh talar osteochondral allografts for treatment of large osteochondral lesions of the talus.新鲜距骨同种异体骨软骨移植治疗距骨大骨软骨病变的中期结果。
J Bone Joint Surg Am. 2012 Jun 20;94(12):1105-10. doi: 10.2106/JBJS.J.02010.
5
Comparison of Osteochondral Autografts and Allografts for Treatment of Recurrent or Large Talar Osteochondral Lesions.自体骨软骨移植与异体骨软骨移植治疗复发性或大型距骨骨软骨损伤的比较
Foot Ankle Int. 2016 Jan;37(1):40-50. doi: 10.1177/1071100715603191. Epub 2015 Sep 2.
6
Midterm results of osteochondral lesions of the talar shoulder treated with fresh osteochondral allograft transplantation.距骨穹隆骨软骨损伤新鲜骨软骨移植治疗的中期结果。
J Bone Joint Surg Am. 2011 Apr 6;93(7):648-54. doi: 10.2106/JBJS.J.00141.
7
Fresh osteochondral allograft for the treatment of cartilage defects of the talus: a retrospective review.新鲜同种异体骨软骨移植治疗距骨软骨缺损:回顾性研究。
J Bone Joint Surg Am. 2011 Sep 7;93(17):1634-40. doi: 10.2106/JBJS.J.00900.
8
Osteochondral transplantation of autologous graft for the treatment of osteochondral lesions of talus: 5- to 7-year follow-up.自体移植骨软骨移植治疗距骨骨软骨损伤:5至7年随访
Knee Surg Sports Traumatol Arthrosc. 2016 Dec;24(12):3722-3729. doi: 10.1007/s00167-014-3389-3. Epub 2014 Oct 19.
9
Results and Functional Outcomes of Structural Fresh Osteochondral Allograft Transfer for Treatment of Osteochondral Lesions of the Talus in a Highly Active Population.结构新鲜骨软骨异体移植治疗高活动量人群距骨骨软骨损伤的结果及功能预后
Foot Ankle Spec. 2017 Apr;10(2):125-132. doi: 10.1177/1938640016666924. Epub 2016 Sep 20.
10
Autologous osteochondral grafting for talar cartilage defects.自体骨软骨移植治疗距骨软骨缺损
Foot Ankle Int. 2002 May;23(5):381-9. doi: 10.1177/107110070202300502.

引用本文的文献

1
The Comparison of the Results of Microfracture and Mosaicplasty in Talus Osteochondral Lesions.距骨骨软骨损伤中微骨折术与镶嵌植骨术结果的比较
Cureus. 2024 May 28;16(5):e61217. doi: 10.7759/cureus.61217. eCollection 2024 May.
2
Characteristics and Clinical Outcomes After Osteochondral Allograft Transplantation for Treating Articular Cartilage Defects: Systematic Review and Single-Arm Meta-analysis of Studies From 2001 to 2020.同种异体骨软骨移植治疗关节软骨缺损后的特征及临床结果:2001年至2020年研究的系统评价和单臂荟萃分析
Orthop J Sports Med. 2023 Sep 21;11(9):23259671231199418. doi: 10.1177/23259671231199418. eCollection 2023 Sep.
3
Prognostic factors for the management of chondral defects of the knee and ankle joint: a systematic review.
膝关节和踝关节软骨缺损的处理的预后因素:系统评价。
Eur J Trauma Emerg Surg. 2023 Apr;49(2):723-745. doi: 10.1007/s00068-022-02155-y. Epub 2022 Nov 7.
4
Osteochondral lesion of the talus: still a problem?距骨骨软骨损伤:仍是一个问题吗?
EFORT Open Rev. 2022 May 31;7(6):337-343. doi: 10.1530/EOR-22-0024.
5
Histological and Inflammatory Cytokine Analysis of Osteochondral Lesions of the Talus After Failed Microfracture: Comparison With Fresh Allograft Controls.微骨折失败后距骨骨软骨损伤的组织学和炎性细胞因子分析:与新鲜同种异体移植对照的比较
Orthop J Sports Med. 2021 Oct 29;9(10):23259671211040535. doi: 10.1177/23259671211040535. eCollection 2021 Oct.
6
Sufficient Cartilage for Most Talar Articular Defects Can Be Harvested From the Non-Loadbearing Talus: A Cadaveric Analysis.对于大多数距骨关节缺损,可从非负重区距骨获取足够的软骨:一项尸体分析。
Arthrosc Sports Med Rehabil. 2021 Jul 24;3(5):e1315-e1320. doi: 10.1016/j.asmr.2021.05.012. eCollection 2021 Oct.
7
Allograft Versus Autograft Osteochondral Transplant for Chondral Defects of the Talus: Systematic Review and Meta-analysis.异体骨软骨移植与自体骨软骨移植治疗距骨软骨缺损:系统评价和荟萃分析。
Am J Sports Med. 2022 Oct;50(12):3447-3455. doi: 10.1177/03635465211037349. Epub 2021 Sep 23.
8
Osteochondral Lesions of the Talus: A Review on Talus Osteochondral Injuries, Including Osteochondritis Dissecans.距骨骨软骨病变:距骨骨软骨损伤综述,包括剥脱性骨软骨炎。
Cartilage. 2021 Dec;13(1_suppl):1380S-1401S. doi: 10.1177/1947603520985182. Epub 2021 Jan 9.
9
Structural Allograft Transplantation for Osteochondral Lesions of the Talus.距骨骨软骨损伤的结构性同种异体移植
JBJS Essent Surg Tech. 2012 Feb 22;2(1):e4. doi: 10.2106/JBJS.ST.K.00040. eCollection 2012 Feb.
10
[Biomechanical study on repair and reconstruction of talar lesion by three-dimensional printed talar components].[三维打印距骨组件修复与重建距骨病变的生物力学研究]
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2018 Mar 15;32(3):306-310. doi: 10.7507/1002-1892.201705068.