The Denver Clinic for Extremities at Risk, Limb Preservation, 1601 E. 19th Ave., Denver, CO 80218, USA.
Foot Ankle Int. 2010 Apr;31(4):277-82. doi: 10.3113/FAI.2010.0277.
Osteochondral lesions of the talar dome (OLT) can be devastating injuries. Many of these problems occur in younger adult patients and can cause permanent joint pain and stiffness. Several treatment methods have been used to treat the symptomatic lesion, including arthroscopic debridement and microfracture, transfer of autologous osteoarticular tissue from the knee or talus (OATS), autologous chondrocyte implantation (ACI), frozen and fresh allograft transplantation.
Eighteen patients underwent fresh talar allograft transplantation with internal fixation for an OLT. Fresh talar allograft transplantation involved arthrotomy of the ankle, often with malleolar osteotomy, and replacement of the talar dome defect with fresh talar allograft tissue and internal fixation. Thirteen of the 18 patients returned for clinical and radiographic examination in addition to completing two validated questionnaires. The other five patients did not return for followup evaluation. The 13 patients who were seen in followup had an average age of 30 (range, 15 to 44) years with a mean followup of 48 months.
There was a significant difference (p < 0.01) between the patients' preoperative and postoperative pain and activity abilities as measured with the Foot Function Index and AOFAS Ankle-Hindfoot questionnaires. Clinical examination and X-rays confirmed healing of the graft.
Based on these results, we conclude that this is a reasonable procedure for younger adult patients with focal osteochondral talar defects that cannot be corrected with curettage and microfracture.
距骨穹隆骨软骨损伤(OLT)可能是破坏性损伤。这些问题大多发生在年轻的成年患者中,可导致永久性关节疼痛和僵硬。已经使用了多种治疗方法来治疗有症状的病变,包括关节镜下清创术和微骨折术、从膝盖或距骨转移自体骨软骨组织(OATS)、自体软骨细胞植入术(ACI)、冷冻和新鲜同种异体移植物移植。
18 例 OLT 患者接受新鲜距骨同种异体移植内固定治疗。新鲜距骨同种异体移植包括踝关节关节切开术,通常伴有踝骨切开术,并使用新鲜距骨同种异体组织和内固定置换距骨穹隆缺损。18 例患者中有 13 例除完成两份有效问卷外,还接受了临床和影像学检查。另外 5 例患者未返回进行随访评估。在随访中看到的 13 例患者的平均年龄为 30 岁(范围为 15 至 44 岁),平均随访时间为 48 个月。
患者术前和术后的疼痛和活动能力(通过足功能指数和 AOFAS 踝关节-后足问卷测量)有显著差异(p < 0.01)。临床检查和 X 射线证实移植物愈合。
基于这些结果,我们得出结论,对于不能通过刮除和微骨折术矫正的年轻成年患者,有局灶性距骨骨软骨缺损,这是一种合理的治疗方法。