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过去一年的受伤风险与血液酒精浓度升高和平均每月饮酒量的暴露时间有关:来自 4 项国家酒精调查的数据(2000 年至 2015 年)。

Risk of Past Year Injury Related to Hours of Exposure to an Elevated Blood Alcohol Concentration and Average Monthly Alcohol Volume: Data from 4 National Alcohol Surveys (2000 to 2015).

机构信息

Alcohol Research Group, Public Health Institute, Emeryville, California.

出版信息

Alcohol Clin Exp Res. 2018 Feb;42(2):360-368. doi: 10.1111/acer.13561. Epub 2017 Dec 19.

Abstract

BACKGROUND

While a strong association exists between alcohol and injury in emergency department (ED) studies, these studies are not representative of the general population.

METHODS

The association of injury with the number of hours of exposure to a blood alcohol concentration (BAC) ≥ 0.05 and average monthly volume in drinks, both based on self-report of quantity and frequency of drinking in the last year, in a merged sample of respondents (n = 29,571) from 4 U.S. National Alcohol Surveys (2000 to 2015) are analyzed. Risk curves based on categorical step function and fractional polynomial modeling were analyzed separately by gender, and by age and race/ethnicity for males.

RESULTS

Risk of injury increased at 1 hour of a BAC exposure of ≥ 0.05 and at an average monthly volume of 1 drink. Risk of injury for spirits increased to an average daily volume of 1 drink, but no association was found for injury risk and average volume for either wine or beer. Risk of injury increased with both exposure hours and monthly volume among males, but little association was found for either consumption measure with risk of injury for females. Among males, increased risk of injury was greater for whites than for blacks or Hispanics for BAC exposure; Hispanics showed a continued elevated risk up to 8 hours of exposure. After peaking at a monthly volume of 1 drink, injury risk decreased substantially for blacks, but was more gradual for whites, while risk increased very slightly for Hispanics to about 4 drinks per day. Males aged 18 to 29 showed the largest increase in risk associated with the number of hours of exposure to a BAC of ≥0.05, with risk doubling at 1 hour of exposure, but subsequently falling.

CONCLUSIONS

While findings here are weaker than those from ED studies and likely due to the context of drinking, risk of injury appears to increase at relatively low levels of consumption, suggesting the importance of preventive efforts to reduce injury not only for heavier drinkers but also for more moderate drinkers.

摘要

背景

在急诊科(ED)研究中,酒精与伤害之间存在很强的关联,但这些研究并不能代表普通人群。

方法

在一个合并的受访者样本(n=29571)中,根据过去一年的饮酒量和饮酒频率的自我报告,分析了损伤与暴露于血液酒精浓度(BAC)≥0.05的小时数以及平均每月饮酒量之间的关系。分别按性别、年龄和种族/民族对男性进行了基于分类阶跃函数和分数多项式模型的风险曲线分析。

结果

暴露于 BAC 1 小时≥0.05和平均每月饮酒量为 1 杯时,受伤风险增加。烈酒的受伤风险增加到平均每天 1 杯,但对于葡萄酒或啤酒,平均饮酒量与受伤风险无关。男性的受伤风险随着暴露时间和每月饮酒量的增加而增加,但女性的两种饮酒量与受伤风险的相关性都很小。在男性中,暴露于 BAC 时,白人的受伤风险高于黑人或西班牙裔,而西班牙裔人则一直处于较高的风险水平,直至暴露 8 小时。黑人的受伤风险在每月饮酒量为 1 杯时达到峰值,随后大幅下降,但白人的下降幅度较缓慢,而西班牙裔人的风险则略有增加,达到每天约 4 杯。18 至 29 岁的男性与暴露于 BAC 时间相关的风险增加幅度最大,暴露 1 小时后风险增加一倍,但随后下降。

结论

尽管这里的发现比 ED 研究中的发现弱,而且可能是由于饮酒环境所致,但受伤风险似乎在相对较低的消费水平下增加,这表明不仅要对酗酒者,而且要对更适度的饮酒者,采取预防措施减少伤害的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/151e/5785417/2afca134c3b1/nihms921450f1.jpg

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