Dana-Farber Cancer Institute, Harvard Medical School, 44 Binney Street, Boston, MA 02115, USA.
Cell Metab. 2010 Apr 7;11(4):257-62. doi: 10.1016/j.cmet.2010.03.005.
Deconvoluting the natural pathway of BAT development has defined key molecular events, which enables researchers to manipulate the amount or activity of brown fat. We review recent advances on the transcriptional regulation of BAT development and discuss the emerging questions.
解析 BAT 发育的自然途径已经明确了关键的分子事件,这使研究人员能够操纵棕色脂肪的数量或活性。我们回顾了 BAT 发育的转录调控的最新进展,并讨论了新出现的问题。