Department of Ophthalmology, Queen's University, Kingston, Ontario, Canada.
Curr Opin Ophthalmol. 2010 May;21(3):227-32. doi: 10.1097/ICU.0b013e3283386706.
To compare health-related quality of life (HRQoL) in American vs. Canadian populations suffering from retinal diseases.
A search of Medline was conducted according to a strategy that combined the MeSH heading 'retinal diseases' with either of 'quality of life' as a MeSH or 'utility' as a keyword. We included studies of American or Canadian patients using any of the National Eye Institute 25-item visual functioning questionnaire (NEI-VFQ-25), visual function index (VF-14), short form health survey (SF-36), or utility to assess HRQoL. A total of 22 studies with American patients and five with Canadian patients were found. There was no significant HRQoL difference found between the American and Canadian patients for any of the HRQoL instruments (P = 0.14-0.80); however, for all instruments mean HRQoL correlated positively with mean visual acuity in the better-seeing eye (P < 0.001).
On the basis of a review of the currently published literature, we were unable to detect significant differences in HRQoL between American and Canadian patients. Further research into the topic is necessary.
目的：比较美国和加拿大视网膜疾病患者的健康相关生活质量（HRQoL）。
发现：根据一项策略，对 Medline 进行了检索，该策略将 MeSH 标题“视网膜疾病”与“生活质量”或“效用”作为 MeSH 或关键字相结合。我们纳入了使用美国国家眼科研究所 25 项视觉功能问卷（NEI-VFQ-25）、视觉功能指数（VF-14）、简明健康调查问卷（SF-36）或效用评估 HRQoL 的美国或加拿大患者的研究。共发现 22 项针对美国患者的研究和 5 项针对加拿大患者的研究。对于任何 HRQoL 工具，美国和加拿大患者的 HRQoL 均无显著差异（P=0.14-0.80）；然而，所有工具的平均 HRQoL 与较好眼的平均视力呈正相关（P<0.001）。
总结：根据对现有文献的综述，我们未能发现美国和加拿大患者的 HRQoL 存在显著差异。需要进一步研究该主题。
