Baharvand Maryam, Maghami Ahmad Ghaem, Azimi Somayyeh, Bastani Hosein, Ahmadieh Azadeh, Taghibakhsh Mehrdad
Department of Oral Medicine, Shaheed Beheshti Medical University, Tehran, Iran.
South Med J. 2010 May;103(5):425-7. doi: 10.1097/SMJ.0b013e3181d7e0d8.
Considering the role of superoxide dismutase (SOD) as one of the most important salivary antioxidant enzymes, this study was performed to compare the level of this enzyme in smokers and nonsmokers.
Unstimulated saliva of 60 volunteers (30 smokers and 30 nonsmokers) was collected. The activity of salivary SOD was measured in each group and compared.
The mean value of superoxide dismutase activity was significantly higher in the smoking group (P < 0.001), while no detectable activity level was found in nonsmokers.
Cigarette smoke leads to an elevation in salivary superoxide dismutase activity.
鉴于超氧化物歧化酶(SOD)作为最重要的唾液抗氧化酶之一的作用,本研究旨在比较吸烟者和非吸烟者体内该酶的水平。
收集60名志愿者(30名吸烟者和30名非吸烟者)的非刺激性唾液。测量每组唾液中SOD的活性并进行比较。
吸烟组超氧化物歧化酶活性的平均值显著更高(P < 0.001),而非吸烟者未检测到活性水平。
香烟烟雾导致唾液中超氧化物歧化酶活性升高。