Shabana Samah, Kawai Azusa, Kai Kenji, Akiyama Kohki, Hayashi Hideo
Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Sakai, Japan.
Biosci Biotechnol Biochem. 2010;74(4):878-80. doi: 10.1271/bbb.90895. Epub 2010 Apr 7.
Methanolic extracts of edible plants and seaweeds were tested for their inhibitory activity against Jack bean urease. Quercetin-4'-O-beta-D-glucopyranoside was isolated from Allium cepa as a urease inhibitor with an IC(50) value of 190 microM-. Quercetin and two quercetin glycosides, avicularin and guaijaverin, were isolated from Psidium guajava as urease inhibitors with respective IC(50) values of 80 microM-, 140 microM-, and 120 microM-.
对食用植物和海藻的甲醇提取物进行了抗洋刀豆脲酶抑制活性测试。从洋葱中分离出槲皮素-4'-O-β-D-吡喃葡萄糖苷作为脲酶抑制剂，其半数抑制浓度（IC50）值为190微摩尔。从番石榴中分离出槲皮素以及两种槲皮素糖苷，即扁蓄苷和桂樱苷，作为脲酶抑制剂，其各自的半数抑制浓度（IC50）值分别为80微摩尔、140微摩尔和120微摩尔。
