来自玉簪的新型甾体皂苷。
New steroidal saponin from Hosta sieboldiana.
作者信息
Yada Hiroshi, Kimura Toshiyuki, Suzuki Masahiro, Ohnishi-Kameyama Mayumi, Shinmoto Hiroshi
机构信息
National Food Research Institute, National Agriculture and Food Research Organization, Tsukuba, Ibaraki, Japan.
出版信息
Biosci Biotechnol Biochem. 2010;74(4):861-4. doi: 10.1271/bbb.90807. Epub 2010 Apr 7.
An extract of the edible parts of Hosta sieboldiana suppressed the growth of P388 mouse leukemic cells. A new steroidal saponin was isolated from Hosta sieboldiana in this study, and the structure was determined by a spectroscopic analysis to be (25R)-3beta-(alpha-L-rhamnopyranosyl-(1-->4)-beta-D-glucopyranosyl-(1-->3)-[beta-D-glucopyranosyl-(1-->2)]-beta-D-glucopyranosyl-(1-->4)-beta-D-galactopyranosyl)-5alpha-spirostan-2alpha-ol.
玉簪可食用部分的提取物抑制了P388小鼠白血病细胞的生长。本研究从玉簪中分离出一种新的甾体皂苷，并通过光谱分析确定其结构为(25R)-3β-(α-L-鼠李糖基-(1→4)-β-D-葡萄糖基-(1→3)-[β-D-葡萄糖基-(1→2)]-β-D-葡萄糖基-(1→4)-β-D-半乳糖基)-5α-螺旋甾烷-2α-醇。
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