结直肠神经内分泌肿瘤的病理研究进展。
Pathologic research update of colorectal neuroendocrine tumors.
机构信息
Department of Pathology, Fudan University Cancer Hospital, 270 Dongan Road, Shanghai 200032, China.
出版信息
World J Gastroenterol. 2010 Apr 14;16(14):1713-9. doi: 10.3748/wjg.v16.i14.1713.
Abstract
Colorectal neuroendocrine tumors (NETs) originate from neuroendocrine cells in the intestinal tract, and represent a small area within oncology, but one which has provided increasing new data during the past years. Although the World Health Organization has determined clinical and histological features to predict prognosis for such tumors, they may not be valid on an individual basis. We aim to give an overview of the recent findings with regard to pathology, molecular genetics and diagnosis of NETs.
摘要
结直肠神经内分泌肿瘤（NETs）起源于肠道内的神经内分泌细胞，在肿瘤学领域中占比较小，但在过去几年中提供了越来越多的新数据。尽管世界卫生组织已经确定了临床和组织学特征来预测此类肿瘤的预后，但这些特征在个体基础上可能并不适用。我们旨在概述 NETs 的病理学、分子遗传学和诊断的最新发现。
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