进行一项优化实验。
Carrying out an optimal experiment.
作者信息
Dauter Zbigniew
机构信息
Synchrotron Radiation Research Section, MCL, National Cancer Institute, Argonne National Laboratory, Argonne, IL 60439, USA.
出版信息
Acta Crystallogr D Biol Crystallogr. 2010 Apr;66(Pt 4):389-92. doi: 10.1107/S0907444909038578. Epub 2010 Mar 24.
Abstract
Diffraction data collection is the last experimental stage in structural crystallography. It has several technical and theoretical aspects and a compromise usually has to be found between various parameters in order to achieve optimal data quality. The influence and importance of various experimental parameters and their consequences are discussed in the context of different data applications, such as molecular replacement, anomalous phasing, high-resolution refinement or searching for ligands.
摘要
衍射数据收集是结构晶体学中的最后一个实验阶段。它有几个技术和理论方面，通常必须在各种参数之间找到折衷方案，以获得最佳数据质量。在不同的数据应用背景下，如分子置换、反常相位法、高分辨率精修或寻找配体，讨论了各种实验参数的影响、重要性及其后果。
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