Socios En Salud Sucursal Perú, Lima, Peru.
AIDS Behav. 2011 Oct;15(7):1454-64. doi: 10.1007/s10461-010-9697-9.
From December 2005 to April 2007, we enrolled 60 adults starting antiretroviral therapy (ART) in Lima, Peru to receive community-based accompaniment with supervised antiretrovirals (CASA), consisting of 12 months of DOT-HAART, as well as microfinance assistance and/or psychosocial support group according to individuals' need. We matched 60 controls from a neighboring district, and assessed final clinical and psychosocial outcomes at 24 months. CASA support was associated with higher rates of virologic suppression and lower mortality. A comprehensive, tailored adherence intervention in the form of community-based DOT-HAART and matched economic and psychosocial support is both feasible and effective for certain individuals in resource-poor settings.
从 2005 年 12 月至 2007 年 4 月,我们招募了 60 名在秘鲁利马开始接受抗逆转录病毒疗法 (ART) 的成年人,为他们提供基于社区的监督抗逆转录病毒治疗 (CASA),包括 12 个月的直接观察治疗下的高效抗逆转录病毒治疗 (DOT-HAART),以及根据个人需要提供小额信贷援助和/或心理社会支持小组。我们在邻近的一个区匹配了 60 名对照者,并在 24 个月时评估最终的临床和心理社会结局。CASA 支持与更高的病毒学抑制率和更低的死亡率相关。在资源匮乏的环境中,以基于社区的 DOT-HAART 为形式的综合、定制的依从性干预措施,以及相匹配的经济和心理社会支持,对于某些人来说是可行且有效的。