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分比双极射频设备与铒玻璃 1550nm 设备治疗萎缩性痤疮瘢痕的比较:一项随机对照的分面临床研究。

Comparison of a fractional bipolar radiofrequency device and a fractional erbium-doped glass 1,550-nm device for the treatment of atrophic acne scars: a randomized split-face clinical study.

机构信息

Department of Dermatology, School of Anti-Aging and Regenerative Medicine, Mae Fah Luang University, Bangkok, Thailand.

出版信息

Dermatol Surg. 2014 Jan;40(1):14-21. doi: 10.1111/dsu.12372. Epub 2013 Nov 25.

DOI:10.1111/dsu.12372
PMID:24267397
Abstract

BACKGROUND

A fractional erbium-doped glass 1,550-nm and a fractional bipolar radiofrequency (RF) device are effective in the treatment of atrophic acne scars.

OBJECTIVE

To compare the clinical effectiveness and side effects of fractional bipolar RF with those of fractional erbium-doped glass in atrophic acne scars treatment.

MATERIALS AND METHODS

Twenty Thai subjects with atrophic acne scars received three split-face monthly treatments, one side with fractional bipolar RF and the other with fractional erbium-doped glass. Three independent physicians and patients evaluated improvement in acne scars 4 weeks after the last treatment. Side effects were also recorded after each treatment.

RESULTS

The study found significant improvement in acne scars after treatment with fractional bipolar RF and with a fractional erbium-doped glass device without a statistically significant difference between the two devices. The side effects of both devices were pain, transient facial erythema, and scab formation. The pain score with fractional erbium-doped glass was higher than that with fractional bipolar RF, but duration of scab shedding was shorter. One case had postinflammatory hyperpigmentation on only the side treated with fractional erbium-doped glass.

CONCLUSION

Fractional bipolar RF and fractional erbium-doped glass have similar effectiveness for the treatment of atrophic acne scars.

摘要

背景

1550nm 铒玻璃分段激光和双极射频(RF)设备在治疗萎缩性痤疮疤痕方面都很有效。

目的

比较双极射频分段与铒玻璃分段在治疗萎缩性痤疮疤痕方面的临床疗效和副作用。

材料和方法

20 名泰国受试者的萎缩性痤疮疤痕接受了每月三次的分割面部治疗,一侧采用双极射频分段,另一侧采用铒玻璃分段。三位独立的医生和患者在最后一次治疗后 4 周评估痤疮疤痕的改善情况。每次治疗后还记录了副作用。

结果

研究发现,双极射频分段和铒玻璃分段治疗后痤疮疤痕均有显著改善,但两种设备之间无统计学差异。两种设备的副作用均为疼痛、短暂性面部红斑和结痂形成。铒玻璃分段的疼痛评分高于双极射频,但结痂脱落的时间更短。只有一侧接受铒玻璃分段治疗的 1 例出现炎症后色素沉着过度。

结论

双极射频分段和铒玻璃分段在治疗萎缩性痤疮疤痕方面具有相似的疗效。

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