Kravvas Georgios, Al-Niaimi Firas
Dermatology, Royal Infirmary of Edinburgh, Edinburgh, UK.
Department of Dermatological Surgery and Lasers, St John's Institute of Dermatology, London, UK.
Scars Burn Heal. 2018 Aug 16;4:2059513118793420. doi: 10.1177/2059513118793420. eCollection 2018 Jan-Dec.
Acne scarring is a very common problem, which can be extensive, and may lead to significant psychosocial morbidity. Multiple types of treatments are used to ameliorate atrophic scars with varying degrees of success. This paper provides an overview of the various energy-based modalities that are commonly employed against acne scarring.
A comprehensive literature search of papers published since 2008 was performed in order to determine the efficacy and adverse reactions of commonly used energy-based treatments against post-acne scarring.
A total of 59 relevant articles were identified covering a multitude of different devices.
Ablative lasers seem to achieve the highest degree of efficacy, albeit this is associated with significant pain and downtime, and the risk for long-term pigmentary changes. Non-ablative fractional photothermolysis (FP) has a much safer profile but cannot achieve as good cosmetic results. The efficacies of fractional radiofrequency microneedling and radiofrequency are slightly inferior to that of FP but offer an even safer adverse profile. Little evidence is available on the remaining devices, with larger studies required in order to reach more solid conclusions.
Multiple devices have been used with varying levels of efficacy and very different safety profiles. There is an overall lack of high-quality evidence about the effects of different interventions. Furthermore, no standardised scale is available for acne scarring, leading to variability in evaluation and interpretation of data in different studies.
痤疮瘢痕是一个非常常见的问题,可能范围广泛,并可能导致严重的社会心理问题。人们使用多种治疗方法来改善萎缩性瘢痕,效果各异。本文概述了常用于治疗痤疮瘢痕的各种基于能量的治疗方式。
对2008年以来发表的论文进行全面的文献检索,以确定常用的基于能量的治疗方法对痤疮后瘢痕的疗效和不良反应。
共识别出59篇相关文章,涵盖了多种不同的设备。
剥脱性激光似乎能达到最高的疗效,尽管这伴随着明显的疼痛和恢复时间,以及长期色素改变的风险。非剥脱性分次光热解(FP)的安全性更高,但美容效果不如前者。分次射频微针和射频的疗效略逊于FP,但不良反应更安全。关于其余设备的证据较少,需要更多大型研究才能得出更可靠的结论。
多种设备用于治疗痤疮瘢痕,疗效水平各异,安全性也大不相同。总体而言,缺乏关于不同干预措施效果的高质量证据。此外,目前尚无针对痤疮瘢痕的标准化量表,导致不同研究中数据的评估和解释存在差异。