刺蒺藜中的新孕甾烷和甾体糖苷

New pregnane and steroidal glycosides from Tribulus terrestris L.

作者信息

Liu Tao, Chen Gang, Yi Guo-Qing, Xu Jian-Kun, Zhang Tian-Long, Hua Hui-Ming, Pei Yue-Hu

机构信息

School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.

出版信息

J Asian Nat Prod Res. 2010 Mar;12(3):209-14. doi: 10.1080/10286020903535419.

DOI:10.1080/10286020903535419

PMID:20390767

Abstract

Three new steroidal saponins were isolated from the fruits of Tribulus terrestris L. Their structures were elucidated by spectroscopic and chemical analysis as 16beta-(4'-methyl-5'-O-beta-D-glucopyranosyl-pentanoxy)-5alpha-pregn-3beta-ol-12,20-dione-3-O-beta-D-glucopyranosyl-(1 --> 2)-beta-D-glucopyranosyl-(1 --> 4)-beta-D-galactopyranoside (1), 2alpha,3beta-dihydroxy-5alpha-pregn-16-en-20-one 3-O-beta-D-glucopyranosyl-(1 --> 4)-beta-D-galactopyranoside (2) and 26-O-beta-D-glucopyranosyl-(25R)-5alpha-furostan-20(22)-en-2alpha,3beta,26-triol-3-O-beta-D-glucopyranosyl-(1 --> 4)-beta-D-galactopyranoside (3).

摘要

从刺蒺藜果实中分离出三种新的甾体皂苷。通过光谱和化学分析确定它们的结构分别为16β-(4'-甲基-5'-O-β-D-吡喃葡萄糖基-戊氧基)-5α-孕甾-3β-醇-12,20-二酮-3-O-β-D-吡喃葡萄糖基-(1→2)-β-D-吡喃葡萄糖基-(1→4)-β-D-吡喃半乳糖苷(1)、2α,3β-二羟基-5α-孕甾-16-烯-20-酮3-O-β-D-吡喃葡萄糖基-(1→4)-β-D-吡喃半乳糖苷(2)和26-O-β-D-吡喃葡萄糖基-(25R)-5α-呋甾烷-20(22)-烯-2α,3β,26-三醇-3-O-β-D-吡喃葡萄糖基-(1→4)-β-D-吡喃半乳糖苷(3)。