来自蒺藜的两种新甾体糖苷

Two new steroidal glucosides from Tribulus terrestris L.

作者信息

Xu Ya-Juan, Xu Tun-Hai, Liu Yue, Xie Sheng-Xu, Si Yun-Shan, Xu Dong-Ming

机构信息

Institute of Traditional Chinese Medicine, Academy of Traditional Chinese Medicine and Material Medica of Jilin Province, Changchun, China.

出版信息

J Asian Nat Prod Res. 2009 Jun;11(6):548-53. doi: 10.1080/10286020902937483.

DOI:10.1080/10286020902937483

PMID:20183289

Abstract

Two new furostanol saponins, tribufurosides D (1) and E (2), were isolated from the fruits of Tribulus terrestris L. With the help of chemical and spectral analyses (IR, MS, 1D, and 2D NMR), the structures of the two new furostanol saponins were established as 26-O-beta-d-glucopyranosyl-(25S)-5alpha-furost-12-one-2alpha,3beta,22alpha,26-tetraol-3-O-beta-d-glucopyranosyl-(1 --> 4)-beta-d-galactopyranoside (1) and 26-O-beta-d-glucopyranosyl-(25R)-5alpha-furost-12-one-2alpha,3beta,22alpha,26-tetraol-3-O-beta-d-glucopyranosyl-(1 --> 4)-beta-d-galactopyranoside (2).

摘要

从刺蒺藜果实中分离出两种新的呋甾烷醇皂苷，刺蒺藜皂苷D（1）和E（2）。借助化学和光谱分析（红外光谱、质谱、一维和二维核磁共振），确定这两种新的呋甾烷醇皂苷的结构分别为26 - O - β - D - 吡喃葡萄糖基 - (25S) - 5α - 呋甾 - 12 - 酮 - 2α,3β,22α,26 - 四醇 - 3 - O - β - D - 吡喃葡萄糖基 - (1→4) - β - D - 吡喃半乳糖苷（1）和26 - O - β - D - 吡喃葡萄糖基 - (25R) - 5α - 呋甾 - 12 - 酮 - 2α,3β,22α,26 - 四醇 - 3 - O - β - D - 吡喃葡萄糖基 - (1→4) - β - D - 吡喃半乳糖苷（2）。