Rommelaere J, Faller D V, Hopkins N
Proc Natl Acad Sci U S A. 1978 Jan;75(1):495-9. doi: 10.1073/pnas.75.1.495.
T1 RNA fingerprints of the genomes of Akv-1 and Akv-2 C-type viruses are indistinguishable and oligonucleotide maps of these viruses are probably the same. Akv-1 and -2 share 55--75% of their large T1-resistant oligonucleotides with four MCF viruses isolated from AKR mice or from NIH Swiss mice that inherit either the Akv-1 or Akv-2 virus-inducing locus of AKR. The majority of Akv oligonucleotides missing from T1 fingerprints of MCFs and the majority of oligonucleotides unique to MCF viruses are clustered and lie at corresponding positions in the 3' half of the oligonucleotide maps of Akv and MCF viruses. The RNA sequences present in different MCF isolates but not present in Akv-viruses are related. These results are consistent with a recombinational origin of MCF viruses, as proposed by Hartley and Rowe and their collaborators.
Akv - 1和Akv - 2 C型病毒基因组的T1 RNA指纹图谱无法区分，并且这些病毒的寡核苷酸图谱可能相同。Akv - 1和 - 2与从AKR小鼠或继承AKR的Akv - 1或Akv - 2病毒诱导位点的NIH瑞士小鼠中分离出的四种MCF病毒共享55 - 75%的大T1抗性寡核苷酸。MCF的T1指纹图谱中缺失的大多数Akv寡核苷酸以及MCF病毒特有的大多数寡核苷酸都聚集在一起，并位于Akv和MCF病毒寡核苷酸图谱3'端的相应位置。不同MCF分离株中存在但Akv病毒中不存在的RNA序列是相关的。这些结果与Hartley、Rowe及其合作者提出的MCF病毒的重组起源一致。
