多囊卵巢综合征中与肥胖相关的炎症介质。
Mediators of inflammation in polycystic ovary syndrome in relation to adiposity.
机构信息
Academic Endocrinology, Diabetes and Metabolism, Hull York Medical School, Michael White Diabetes Centre, 220-236 Analby Road, Hull Royal Infirmary, Hull HU32JZ, UK.
出版信息
Mediators Inflamm. 2010;2010:758656. doi: 10.1155/2010/758656. Epub 2010 Apr 8.
Abstract
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age group and is associated with a higher cardiovascular risk. Obesity, mainly visceral adiposity, is prevalent in patients with PCOS. Obesity is associated with low-grade inflammation and raised inflammatory cytokines, both of which are also described in patients with PCOS. In this paper, the potential relationships between fat distribution, adipocyte dysfunction and, altered inflammatory markers in patients with PCOS have been discussed.
摘要
多囊卵巢综合征（PCOS）是育龄妇女常见的内分泌疾病，与心血管风险增加相关。肥胖，主要是内脏脂肪过多，在 PCOS 患者中很常见。肥胖与低度炎症和炎症细胞因子升高有关，这两种情况也在 PCOS 患者中有所描述。本文讨论了 PCOS 患者的脂肪分布、脂肪细胞功能障碍和炎症标志物改变之间的潜在关系。
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