Gastroenterology and Endoscopy Unit, University of Parma, via Gramsci 14, 43100 Parma, Italy.
World J Gastroenterol. 2010 Apr 21;16(15):1924-7. doi: 10.3748/wjg.v16.i15.1924.
The association of cystic fibrosis and Crohn's disease (CD) is well known, but to date, there are very few cases in the literature of patients suffering from mucoviscidosis who have required treatment with infliximab. We report the case of a 23-year-old patient suffering from cystic fibrosis and severe CD treated successfully with infliximab without any infective complications or worsening of the pulmonary disease and with a long term (2 years) complete remission.
囊性纤维化和克罗恩病(CD)的关联是众所周知的,但迄今为止,文献中仅有极少数患有粘液化脓性疾病且需要英夫利昔单抗治疗的患者病例。我们报告了一例 23 岁的囊性纤维化患者,并发严重的 CD,成功地接受了英夫利昔单抗治疗,没有任何感染并发症,也没有使肺部疾病恶化,并且长期(2 年)完全缓解。