Hutley E J, Green A D
London Deanery.
J R Army Med Corps. 2009 Dec;155(4):315-9. doi: 10.1136/jramc-155-04-14.
Infection is an important consideration in war wounds. Improvements in survival and use of increasingly broad-spectrum antibiotics have led to new challenges with novel pathogens and conventional pathogens with multiple drug resistance patterns.. learnt in conflicts centuries ago. The cornerstone remains early, appropriate and repeated surgery. Antimicrobial agents contribute a very minor part to overall patient outcome, but prudent use of antibiotics and good infection control is essential to prevent establishment and spread of hospital-acquired infections. Research in progress will provide an evidence base for antibiotic and infection control policies and baseline data for research into novel wound management strategies.
感染是战伤中一个重要的考量因素。生存率的提高以及越来越广泛地使用广谱抗生素，带来了与新型病原体以及具有多种耐药模式的传统病原体相关的新挑战……这是在几个世纪前的冲突中所学到的。关键仍然是早期、恰当且反复的手术。抗菌药物对患者总体预后的作用非常小，但谨慎使用抗生素和做好感染控制对于预防医院获得性感染的发生和传播至关重要。正在进行的研究将为抗生素和感染控制政策提供证据基础，并为新型伤口管理策略的研究提供基线数据。
