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接受轻度治疗性低温治疗患者的无创连续脑温度监测:一项观察性试点研究。

Non-invasive continuous cerebral temperature monitoring in patients treated with mild therapeutic hypothermia: an observational pilot study.

机构信息

Department of Emergency Medicine, Medical University of Vienna, Währinger Gürtel 18-20/6D, Wien, Austria.

出版信息

Resuscitation. 2010 Jul;81(7):861-6. doi: 10.1016/j.resuscitation.2010.03.018. Epub 2010 Apr 15.

DOI:10.1016/j.resuscitation.2010.03.018
PMID:20398992
Abstract

AIM OF THE STUDY

To investigate if body temperature as measured with a prototype of a non-invasive continuous cerebral temperature sensor using the zero-heat-flow method to reflect the oesophageal temperature (core temperature) during mild therapeutic hypothermia after cardiac arrest.

METHODS

In patients over 18 years old with restoration of spontaneous circulation after cardiac arrest, a temperature sensor that uses the zero-heat-flow principle was placed on the forehead during the periods of cooling and re-warming. This temperature was compared to oesophageal temperature as the primary temperature-monitoring site. To assess agreement, we used the Bland-Altman approach and Lin's concordance correlation coefficient.

RESULTS

From September 2008 to April 2009, data from 19 patients were analysed. The median time from restoration of spontaneous circulation until temperature sensor application was 53min (interquartile range, 31; 96). All sensors were removed when a core temperature of 36 degrees C was reached. These measurements were in agreement with oesophageal temperature measurements. No allergic reaction, rash or other irritation occurred on the skin around or under the probes. Bland-Altman results showed a bias of -0.12 degrees C and 95% limits of agreement of -0.59 and +0.36 degrees C. Lin's concordance correlation coefficient was 0.98.

CONCLUSIONS

Body temperature measurements using a non-invasive continuous cerebral temperature sensor prototype that uses the zero-heat-flow method accurately reflected oesophageal temperature measurements during mild therapeutic hypothermia in patients with restoration of spontaneous circulation after cardiac arrest.

摘要

研究目的

探究使用零热流法测量的非侵入性连续脑温传感器原型,是否可以反映心脏骤停后轻度治疗性低体温期间的食管温度(核心温度)。

方法

在 18 岁以上的患者中,在心脏骤停后自主循环恢复期间,将使用零热流原理的温度传感器放置在前额上,用于冷却和复温期间。该温度与食管温度(主要监测部位)进行比较。为了评估一致性,我们使用 Bland-Altman 方法和 Lin 的一致性相关系数。

结果

2008 年 9 月至 2009 年 4 月,对 19 名患者的数据进行了分析。从自主循环恢复到温度传感器应用的中位数时间为 53 分钟(四分位距,31;96)。当核心温度达到 36°C 时,所有传感器均被移除。这些测量结果与食管温度测量结果一致。在探头周围或下方的皮肤周围未发生过敏反应、皮疹或其他刺激。Bland-Altman 结果显示偏倚为-0.12°C,95%一致性界限为-0.59°C 和+0.36°C。Lin 的一致性相关系数为 0.98。

结论

使用零热流法测量的非侵入性连续脑温传感器原型,可准确反映心脏骤停后自主循环恢复患者轻度治疗性低体温期间的食管温度测量值。

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